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Medicines labeled for the same conditions

Alternatives to fluocinolone

15 other medicines are given the same way (topical) and in the same FDA class as fluocinolone or labeled mainly for the same use (psoriasis); 10 are in its class, corticosteroids: hydrocortisone, clobetasol, betamethasone, desoximetasone and 6 more; the others include 1 retinoid, 1 vitamin d analog and 1 vitamin d3 analog (FDA labels read October 8, 2026). In the same class, the lowest pharmacy cost is $0.0613 per gram (Hydrocortisone 1% cream) (what pharmacies paid in the NADAC survey; strengths differ).

Which medicines are labeled for the same conditions as fluocinolone?

Psoriasis lists all 38 medicines labeled for it, by any route. Each row shows the conditions both labels name. They are listed as public records, not as substitutes: whether one can replace another depends on the person and is a prescriber's decision.

Medicine and FDA classShared indicationGeneric labelers (topical)Pharmacy costBoxed warningShortage
Fluocinolonecorticosteroidthis medicine15 labelers$0.171 per mL 0.01% scalp oilNoNo current entry
Hydrocortisonecorticosteroid · same classEczema (atopic dermatitis)30 labelers$0.0613 per gram 1% creamNoA presentation being discontinued
Clobetasolcorticosteroid · same classPsoriasis40 labelers$0.126 per gram 0.05% ointmentNoNo current entry
Betamethasonecorticosteroid · same classPsoriasis26 labelers$0.418 per gram 0.05% creamNoNo current entry
Desoximetasonecorticosteroid · same classPsoriasis13 labelers$0.369 per gram 0.25% ointmentNoNo current entry
Desonidecorticosteroid · same classEczema (atopic dermatitis)12 labelers$0.252 per gram 0.05% creamNoNo current entry
Fluticasonecorticosteroid · same classEczema (atopic dermatitis)8 labelers$0.243 per gram 0.05% creamNoNo current entry
Halobetasolcorticosteroid · same classPsoriasis6 labelers$0.620 per gram 0.05% ointmntNoNo current entry
Betamethasone and calcipotrienevitamin d analog · same classPsoriasis5 labelers$1.81 per gram 0.005%-0.064% ointmentNoNo current entry
Dexamethasonecorticosteroid · same classEczema (atopic dermatitis)none listedn/aNoIn shortage
Halobetasol and tazaroteneretinoid · same classPsoriasisnone listedn/aNoNo current entry
Coal tarPsoriasisnone listed$0.0088 per mL 0.5% shampooNoNo current entry
TazaroteneretinoidPsoriasis6 labelers$6.11 per gram 0.1% gelNoNo current entry
Calcipotrienevitamin d analogPsoriasis6 labelers$1.05 per gram 0.005% creamNoNo current entry
Calcitriolvitamin d3 analogPsoriasisnone listedn/aNoA presentation being discontinued
Tapinarofaryl hydrocarbon receptor agonistPsoriasis, Eczema (atopic dermatitis)none listed$25.23 per gram 1% creamNoNo current entry

Source: FDA drug labels (indications) via openFDA; FDA NDC Directory; CMS NADAC of October 7, 2026; FDA Drug Shortage Database (FDA files October 8, 2026)

What do pharmacies pay for each?

The headline NADAC price per unit of each medicine's most widely listed form; strengths differ, so compare like with like on each record.

Source: CMS National Average Drug Acquisition Cost (NADAC) survey, October 7, 2026: what retail pharmacies paid per unit; not a counter price

What next?

Fluocinolone: the full record
label, generics, price, shortages, recalls
Fluocinolone vs hydrocortisone
two records side by side
Fluocinolone vs clobetasol
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Betamethasone vs fluocinolone
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