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Medicines labeled for the same conditions

Alternatives to entrectinib

26 other medicines are given the same way (oral) and in the same FDA class as entrectinib or labeled mainly for the same use (lung cancer); the others include 18 kinase inhibitors and 1 topoisomerase inhibitor (FDA labels read October 8, 2026).

Which medicines are labeled for the same conditions as entrectinib?

The first 24 of the 26, the same class first. Lung cancer lists all 55 medicines labeled for it, by any route. Each row shows the conditions both labels name. They are listed as public records, not as substitutes: whether one can replace another depends on the person and is a prescriber's decision.

Medicine and FDA classShared indicationGeneric labelers (oral)Pharmacy costBoxed warningShortage
Entrectinibthis medicinenone listedn/aNoNo current entry
Erlotinibkinase inhibitorLung cancer10 labelersn/aNoNo current entry
Afatinibkinase inhibitorLung cancer1 labelern/aNoNo current entry
Selpercatinibkinase inhibitorLung cancernone listedn/aNoNo current entry
Crizotinibkinase inhibitorLung cancernone listedn/aNoNo current entry
Gefitinibkinase inhibitorLung cancer4 labelersn/aNoNo current entry
Brigatinibkinase inhibitorLung cancernone listedn/aNoNo current entry
Dabrafenibkinase inhibitorLung cancernone listedn/aNoNo current entry
DacomitinibLung cancernone listedn/aNoA presentation being discontinued
Lorlatinibkinase inhibitorLung cancernone listedn/aNoA presentation being discontinued
SotorasibLung cancernone listedn/aNoNo current entry
Trametinibkinase inhibitorLung cancernone listedn/aNoNo current entry
Capmatinibkinase inhibitorLung cancernone listedn/aNoNo current entry
EnsartinibLung cancernone listedn/aNoNo current entry
Lazertinibkinase inhibitorLung cancernone listedn/aNoNo current entry
Repotrectinibkinase inhibitorLung cancernone listedn/aNoNo current entry
Topotecantopoisomerase inhibitorLung cancernone listedn/aYesNo current entry
ZidesamtinibLung cancernone listedn/aNoNo current entry
AdagrasibLung cancernone listedn/aNoNo current entry
Alectinibkinase inhibitorLung cancernone listedn/aNoNo current entry
BinimetinibLung cancernone listedn/aNoNo current entry
Ceritinibkinase inhibitorLung cancernone listedn/aNoNo current entry
Pralsetinibkinase inhibitorLung cancernone listedn/aYesNo current entry
SevabertinibLung cancernone listedn/aNoNo current entry
Taletrectinib adipatekinase inhibitorLung cancernone listedn/aNoNo current entry

Source: FDA drug labels (indications) via openFDA; FDA NDC Directory; CMS NADAC of October 7, 2026; FDA Drug Shortage Database (FDA files October 8, 2026)

What next?

Entrectinib: the full record
label, generics, price, shortages, recalls