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Medicines labeled for the same conditions

Alternatives to eluxadoline

5 other medicines are given the same way (oral) and in the same FDA class as eluxadoline or labeled mainly for the same use (irritable bowel syndrome); the others include 1 anticholinergic, 1 benzodiazepine and 1 rifamycin antibacterial (FDA labels read October 8, 2026).

Which medicines are labeled for the same conditions as eluxadoline?

Irritable bowel syndrome lists all 7 medicines labeled for it, by any route. Each row shows the conditions both labels name. They are listed as public records, not as substitutes: whether one can replace another depends on the person and is a prescriber's decision.

Medicine and FDA classShared indicationGeneric labelers (oral)Pharmacy costBoxed warningShortage
Eluxadolinemu-opioid receptor agonistthis medicinenone listed$28.09 per tablet 100 mg tabletNoNo current entry
DicyclomineanticholinergicIrritable bowel syndrome37 labelers$0.059 per tablet 20 mg tabletNoNo current entry
Chlordiazepoxide and clidiniumbenzodiazepineIrritable bowel syndrome12 labelers$0.256 per capsule Chlordiazepoxide-clidinium capsuleYesNo current entry
Rifaximinrifamycin antibacterialIrritable bowel syndrome, Diarrheanone listedn/aNoNo current entry
Tenapanorsodium-hydrogen exchanger 3 inhibitorIrritable bowel syndromenone listed$32.54 per tablet 50 mg tabletNoNo current entry
Linaclotideguanylate cyclase-c agonistIrritable bowel syndromenone listed$9.02 per capsule 145 mcg capsuleYesNo current entry

Source: FDA drug labels (indications) via openFDA; FDA NDC Directory; CMS NADAC of October 7, 2026; FDA Drug Shortage Database (FDA files October 8, 2026)

What do pharmacies pay for each?

The headline NADAC price per unit of each medicine's most widely listed form; strengths differ, so compare like with like on each record.

Source: CMS National Average Drug Acquisition Cost (NADAC) survey, October 7, 2026: what retail pharmacies paid per unit; not a counter price

What next?

Eluxadoline: the full record
label, generics, price, shortages, recalls