Medicines labeled for the same conditions
Alternatives to drospirenone and estradiol
5 other medicines are given the same way (oral) and in the same FDA class as drospirenone and estradiol or labeled mainly for the same use (menopause symptoms); 2 are in its class, estrogens: ethinyl estradiol and norethindrone and estrogens conjugated; the others include 1 neurokinin 3 receptor antagonist and 1 estrogen agonist/antagonist (FDA labels read October 8, 2026). In the same class, the lowest pharmacy cost is $0.181 per microgestin 21 1-20 tablet (what pharmacies paid in the NADAC survey; strengths differ).
Which medicines are labeled for the same conditions as drospirenone and estradiol?
Menopause symptoms lists all 11 medicines labeled for it, by any route. Each row shows the conditions both labels name. They are listed as public records, not as substitutes: whether one can replace another depends on the person and is a prescriber's decision.
| Medicine and FDA class | Shared indication | Generic labelers (oral) | Pharmacy cost | Boxed warning | Shortage |
|---|---|---|---|---|---|
| Drospirenone and estradiolestrogen | this medicine | none listed | $6.37 per tablet 0.25 mg-0.5 mg tablet | Yes | No current entry |
| Ethinyl estradiol and norethindroneestrogen · same class | Menopause symptoms | 15 labelers | $0.181 per tablet 21 1-20 tablet | Yes | No current entry |
| Estrogens conjugatedestrogen · same class | Menopause symptoms | 1 labeler | $5.47 per tablet 0.625 mg tablet | Yes | No current entry |
| Fezolinetantneurokinin 3 receptor antagonist | Menopause symptoms | none listed | $18.58 per tablet 45 mg tablet | Yes | No current entry |
| Elinzanetant | Menopause symptoms | none listed | $9.97 per capsule 60 mg capsule | No | No current entry |
| Ospemifeneestrogen agonist/antagonist | Menopause symptoms | none listed | $8.17 per tablet 60 mg tablet | Yes | No current entry |
Source: FDA drug labels (indications) via openFDA; FDA NDC Directory; CMS NADAC of October 7, 2026; FDA Drug Shortage Database (FDA files October 8, 2026)
What do pharmacies pay for each?
The headline NADAC price per unit of each medicine's most widely listed form; strengths differ, so compare like with like on each record.
Source: CMS National Average Drug Acquisition Cost (NADAC) survey, October 7, 2026: what retail pharmacies paid per unit; not a counter price
What next?
- Drospirenone and estradiol: the full record
- label, generics, price, shortages, recalls