Alternatives to donepezil
2 same-class SPL records vs donepezil - uses, FAERS reaction fields, and OTC/Rx flags from public FDA sources.
Brand: Aricept
How to read a high-report FAERS peer set
donepezil ranks in the upper FAERS-volume third of the corpus (#175 of 524); 2 same-class peers are listed for field comparison only. Labeled indication field for donepezil: Donepezil treats dementia in people with Alzheimer's disease.
Top FAERS reaction fields for donepezil total 17,920 reports across 10 reactions, set beside galantamine, rivastigmine. Counts are exposure-weighted submissions, not per-patient risk.
About donepezil
Donepezil is a medicine used to treat dementia caused by Alzheimer's disease. It can help improve memory and thinking.
Used for: Donepezil treats dementia in people with Alzheimer's disease. It can help with mild, moderate, and severe forms of the disease. This medicine can improve memory, awareness, and the ability to function.
2 Acetylcholinesterase Inhibitor peers (wide set)
galantamine
RxRazadyne
This medicine treats mild to moderate Alzheimer's disease. Alzheimer's can affect memory, thinking, and behavior. Galantamine may help improve these symptoms.
rivastigmine
RxExelon
This medicine treats mild to moderate dementia caused by Alzheimer's disease. It also treats mild to moderate dementia linked to Parkinson's disease. Dementia affects memory, thinking, and the ability to do daily activities.
donepezil vs galantamine & rivastigmine · FAERS reaction fields
FAERS top-reaction field "Fall" shows the widest count spread between donepezil and galantamine, rivastigmine in this extract (1,301-report gap on that field). Counts are exposure-weighted submissions, not prevalence rates.
| Side Effect | donepezil | galantamine | rivastigmine |
|---|---|---|---|
| Fall | 2,965 | 375 | 1,664 |
| Death | 2,020 | - | 2,177 |
| Confusional State | 1,893 | 75 | 1,258 |
| Diarrhoea | 1,738 | - | 640 |
| Dizziness | 1,732 | - | 771 |
| Fatigue | 1,686 | - | 637 |
| Nausea | 1,599 | - | 827 |
| Hallucination | 1,481 | 77 | 1,365 |
"-" means no reports for that reaction. Report counts reflect total FAERS submissions, not prevalence rates.
donepezil FAERS volume vs class peers
FAERS volume band
donepezil is FAERS corpus rank #175 of 524 (high volume tercile). Top-reaction field total: 17,920.
Frequently Asked Questions
Where does donepezil sit in FAERS report volume vs Acetylcholinesterase Inhibitor peers? ▼
Registry note: FAERS counts are voluntary reports and do not establish causation or risk rates. This information is for educational purposes only and is not a substitute for professional medical advice. Do not stop or change your medication without talking to your doctor or pharmacist.
Field note for donepezil: see also the generic vs brand label guide when reading Aricept SPL strings.
Read our methodology - how this data is sourced, computed, and verified.