Alternatives to dofetilide
2 same-class SPL records vs dofetilide - uses, FAERS reaction fields, and OTC/Rx flags from public FDA sources.
Brand: Tikosyn
About dofetilide
Dofetilide (Tikosyn) helps keep your heart in a normal rhythm if you have atrial fibrillation or atrial flutter. It can also help convert these abnormal rhythms back to normal.
Used for: This medicine is used to maintain a normal heart rhythm if you have atrial fibrillation or atrial flutter for more than a week, and your heart has been returned to a normal rhythm. It can also convert atrial fibrillation and atrial flutter to a normal rhythm. This medicine is for people who have bothersome symptoms from their atrial fibrillation or flutter.
2 Class III Antiarrhythmic peers (wide set)
amiodarone
RxCordarone, Pacerone
This medicine treats very fast, irregular heartbeats in the ventricles (lower chambers of the heart). It is used when these irregular heartbeats are life-threatening. It is also used when other medicines don't work well enough or cause too many side effects. This medicine is for adults.
dronedarone
RxMultaq
Multaq is used to lower the risk of hospitalization if you have atrial fibrillation (AFib). AFib is an irregular heartbeat. This medicine is for people who used to have AFib, but are now in a normal heart rhythm.
dofetilide vs amiodarone & dronedarone · FAERS reaction fields
FAERS top-reaction field "Dyspnoea" shows the widest count spread between dofetilide and amiodarone, dronedarone in this extract (555-report gap on that field). Counts are exposure-weighted submissions, not prevalence rates.
| Side Effect | dofetilide | amiodarone | dronedarone |
|---|---|---|---|
| Atrial Fibrillation | 1,058 | 594 | 1,420 |
| Dyspnoea | 603 | 1,158 | 838 |
| Dizziness | 552 | 572 | 449 |
| Fatigue | 520 | 895 | 615 |
| Death | 478 | 393 | - |
| Electrocardiogram Qt Prolonged | 443 | - | - |
| Headache | 387 | - | 225 |
| Malaise | 319 | - | 218 |
"-" means no reports for that reaction. Report counts reflect total FAERS submissions, not prevalence rates.
dofetilide peer mix vs class inventory
Peer mix
0 OTC and 2 Rx SPL records in this peer set (2 total). Class inventory for Class III Antiarrhythmic: 3 drugs.
Frequently Asked Questions
What same-class SPL records sit beside dofetilide? ▼
Reading a wide Class III Antiarrhythmic peer set (2 records)
dofetilide (Tikosyn) sits in a wide Class III Antiarrhythmic peer set (2 of 2 class peers shown). Labeled indication field for dofetilide: This medicine is used to maintain a normal heart rhythm if you have atrial fibrillation or atrial flutter for more than a week, and your heart has been returned to a normal rhythm.
Top FAERS reaction fields for dofetilide total 4,973 reports across 10 reactions, set beside amiodarone, dronedarone. Counts are exposure-weighted submissions, not per-patient risk.
Registry note: Therapeutic-class peer lists are registry indexes, not prescribing advice. This information is for educational purposes only and is not a substitute for professional medical advice. Do not stop or change your medication without talking to your doctor or pharmacist.
Field note for dofetilide: see also the generic vs brand label guide when reading Tikosyn SPL strings.
Read our methodology - how this data is sourced, computed, and verified.