Medicines labeled for the same conditions
Alternatives to dextromethorphan and guaifenesin and naproxen
4 other medicines are given the same way (oral) and in the same FDA class as dextromethorphan and guaifenesin and naproxen or labeled mainly for the same use (fever); 2 are in its class, expectorants: ibuprofen and acetaminophen and aspirin and caffeine (FDA labels read October 8, 2026). In the same class, the lowest pharmacy cost is $0.0573 per ibuprofen 800 mg tablet (what pharmacies paid in the NADAC survey; strengths differ).
Which medicines are labeled for the same conditions as dextromethorphan and guaifenesin and naproxen?
Fever lists all 8 medicines labeled for it, by any route. Each row shows the conditions both labels name. They are listed as public records, not as substitutes: whether one can replace another depends on the person and is a prescriber's decision.
| Medicine and FDA class | Shared indication | Generic labelers (oral) | Pharmacy cost | Boxed warning | Shortage |
|---|---|---|---|---|---|
| Dextromethorphan and guaifenesin and naproxenexpectorant | this medicine | none listed | n/a | No | No current entry |
| Ibuprofennonsteroidal anti-inflammatory drug · same class | Fever | 273 labelers | $0.0573 per tablet 800 mg tablet | Yes | No current entry |
| Acetaminophen and aspirin and caffeineplatelet aggregation inhibitor · same class | Fever | 39 labelers | $0.0648 per unit 250-250-65 mg cplt | No | No current entry |
| Acetaminophen | Fever | 79 labelers | $0.0339 per unit 500 mg caplet | Yes | No current entry |
| Meclofenamate | Fever | 1 labeler | n/a | Yes | No current entry |
Source: FDA drug labels (indications) via openFDA; FDA NDC Directory; CMS NADAC of October 7, 2026; FDA Drug Shortage Database (FDA files October 8, 2026)
What do pharmacies pay for each?
The headline NADAC price per unit of each medicine's most widely listed form; strengths differ, so compare like with like on each record.
Source: CMS National Average Drug Acquisition Cost (NADAC) survey, October 7, 2026: what retail pharmacies paid per unit; not a counter price
What next?
- Dextromethorphan and guaifenesin and naproxen: the full record
- label, generics, price, shortages, recalls