Medicines labeled for the same conditions
Alternatives to clobetasol
11 other medicines are given the same way (topical) and in the same FDA class as clobetasol or labeled mainly for the same use (psoriasis); 6 are in its class, corticosteroids: betamethasone, fluocinolone, desoximetasone, halobetasol and 2 more; the others include 1 retinoid, 1 vitamin d analog and 1 vitamin d3 analog (FDA labels read October 8, 2026). In the same class, the lowest pharmacy cost is $0.171 per mL (Fluocinolone 0.01% scalp oil) (what pharmacies paid in the NADAC survey; strengths differ).
Which medicines are labeled for the same conditions as clobetasol?
Psoriasis lists all 38 medicines labeled for it, by any route. Each row shows the conditions both labels name. They are listed as public records, not as substitutes: whether one can replace another depends on the person and is a prescriber's decision.
| Medicine and FDA class | Shared indication | Generic labelers (topical) | Pharmacy cost | Boxed warning | Shortage |
|---|---|---|---|---|---|
| Clobetasolcorticosteroid | this medicine | 40 labelers | $0.126 per gram 0.05% ointment | No | No current entry |
| Betamethasonecorticosteroid · same class | Psoriasis | 26 labelers | $0.418 per gram 0.05% cream | No | No current entry |
| Fluocinolonecorticosteroid · same class | Psoriasis | 15 labelers | $0.171 per mL 0.01% scalp oil | No | No current entry |
| Desoximetasonecorticosteroid · same class | Psoriasis | 13 labelers | $0.369 per gram 0.25% ointment | No | No current entry |
| Halobetasolcorticosteroid · same class | Psoriasis | 6 labelers | $0.620 per gram 0.05% ointmnt | No | No current entry |
| Betamethasone and calcipotrienevitamin d analog · same class | Psoriasis | 5 labelers | $1.81 per gram 0.005%-0.064% ointment | No | No current entry |
| Halobetasol and tazaroteneretinoid · same class | Psoriasis | none listed | n/a | No | No current entry |
| Coal tar | Psoriasis | none listed | $0.0088 per mL 0.5% shampoo | No | No current entry |
| Tazaroteneretinoid | Psoriasis | 6 labelers | $6.11 per gram 0.1% gel | No | No current entry |
| Calcipotrienevitamin d analog | Psoriasis | 6 labelers | $1.05 per gram 0.005% cream | No | No current entry |
| Calcitriolvitamin d3 analog | Psoriasis | none listed | n/a | No | A presentation being discontinued |
| Tapinarofaryl hydrocarbon receptor agonist | Psoriasis | none listed | $25.23 per gram 1% cream | No | No current entry |
Source: FDA drug labels (indications) via openFDA; FDA NDC Directory; CMS NADAC of October 7, 2026; FDA Drug Shortage Database (FDA files October 8, 2026)
What do pharmacies pay for each?
The headline NADAC price per unit of each medicine's most widely listed form; strengths differ, so compare like with like on each record.
Source: CMS National Average Drug Acquisition Cost (NADAC) survey, October 7, 2026: what retail pharmacies paid per unit; not a counter price
What next?
- Clobetasol: the full record
- label, generics, price, shortages, recalls
- Betamethasone vs clobetasol
- two records side by side
- Fluocinolone vs clobetasol
- two records side by side
- Clobetasol vs desoximetasone
- two records side by side
- Clobetasol vs halobetasol
- two records side by side