Medicines labeled for the same conditions
Alternatives to alprazolam
11 other medicines are given the same way (oral) and in the same FDA class as alprazolam or labeled mainly for the same use (anxiety); 7 are in its class, benzodiazepines: clonazepam, lorazepam, diazepam, chlordiazepoxide and 3 more; the others include 1 antihistamine and 1 tricyclic antidepressant (FDA labels read October 8, 2026). In the same class, the lowest pharmacy cost is $0.0244 per clonazepam 1 mg tablet (what pharmacies paid in the NADAC survey; strengths differ).
Which medicines are labeled for the same conditions as alprazolam?
Anxiety lists all 22 medicines labeled for it, by any route. Each row shows the conditions both labels name. They are listed as public records, not as substitutes: whether one can replace another depends on the person and is a prescriber's decision.
| Medicine and FDA class | Shared indication | Generic labelers (oral) | Pharmacy cost | Boxed warning | Shortage |
|---|---|---|---|---|---|
| Alprazolambenzodiazepine | this medicine | 30 labelers | $0.0236 per tablet 0.25 mg tablet | Yes | No current entry |
| Clonazepambenzodiazepine · same class | Anxiety | 31 labelers | $0.0244 per tablet 1 mg tablet | Yes | In shortage |
| Lorazepambenzodiazepine · same class | Anxiety | 33 labelers | $0.0344 per tablet 0.5 mg tablet | Yes | In shortage |
| Diazepambenzodiazepine · same class | Anxiety | 32 labelers | $0.0283 per tablet 10 mg tablet | Yes | No current entry |
| Chlordiazepoxidebenzodiazepine · same class | Anxiety | 15 labelers | $0.158 per capsule 25 mg capsule | Yes | No current entry |
| Clorazepatebenzodiazepine · same class | Anxiety | 8 labelers | $0.524 per tablet 3.75 mg tablet | Yes | No current entry |
| Oxazepambenzodiazepine · same class | Anxiety | 6 labelers | $0.725 per capsule 10 mg capsule | Yes | No current entry |
| Amitriptyline and chlordiazepoxidetricyclic antidepressant · same class | Anxiety | 1 labeler | $1.20 per unit 5-12.5 | Yes | No current entry |
| Buspirone | Anxiety | 49 labelers | $0.043 per tablet 15 mg tablet | No | No current entry |
| Hydroxyzineantihistamine | Anxiety | 59 labelers | $0.0326 per tablet 25 mg tablet | No | No current entry |
| Meprobamate | Anxiety | 3 labelers | $5.89 per tablet 400 mg tablet | No | No current entry |
| Amitriptyline and perphenazinetricyclic antidepressant | Anxiety | 1 labeler | n/a | Yes | No current entry |
Source: FDA drug labels (indications) via openFDA; FDA NDC Directory; CMS NADAC of October 7, 2026; FDA Drug Shortage Database (FDA files October 8, 2026)
What do pharmacies pay for each?
The headline NADAC price per unit of each medicine's most widely listed form; strengths differ, so compare like with like on each record.
Source: CMS National Average Drug Acquisition Cost (NADAC) survey, October 7, 2026: what retail pharmacies paid per unit; not a counter price
What next?
- Alprazolam: the full record
- label, generics, price, shortages, recalls
- Alprazolam vs clonazepam
- two records side by side
- Alprazolam vs lorazepam
- two records side by side
- Alprazolam vs diazepam
- two records side by side
- Chlordiazepoxide vs alprazolam
- two records side by side