What the FDA labels say about taking them together
Memantine and trimethoprim
Neither FDA label names the other in its interaction, contraindication or warning sections. A label lists the interactions its studies and reports found; it is not a complete list, so ask a pharmacist before combining medicines. Labels read October 8, 2026.
Check it at the source: the memantine FDA label on DailyMed (effective November 1, 2018, Actavis Pharma, Inc.); the trimethoprim FDA label on DailyMed (effective January 26, 2024, Dr. Reddy's Labratories Inc.).
What does the memantine label say about trimethoprim?
Memantine's label (effective November 1, 2018) does not name trimethoprim in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (memantine hydrochloride), NDA021487 (Abbvie), as published by Actavis Pharma, Inc., effective November 1, 2018 (SPL set 72973b46-f307-4a9e-8fb1-ad2cbccfd736), via openFDA; the full label on DailyMed
What does the trimethoprim label say about memantine?
Trimethoprim's label (effective January 26, 2024) does not name memantine in these sections. A label lists what its studies and reports found; it is not a complete list.
Source: FDA drug label (Trimethoprim), NDA018679 (Dr Reddys Labs Sa), as published by Dr. Reddy's Labratories Inc., effective January 26, 2024 (SPL set 73ccebc1-7412-2424-d62c-a5180ec52d81), via openFDA; the full label on DailyMed
A pharmacist or prescriber can say whether these two medicines suit one person together; PlainMeds does not grade interactions.
Both medicines on the record
| Memantine | Trimethoprim | |
|---|---|---|
| Labeled for | Alzheimer's disease | Bacterial infections, Urinary tract infections |
| Boxed warning | No | No |
| Pharmacy cost (NADAC) | $0.063 per tablet 10 mg tablet | $1.31 per tablet 100 mg tablet |
| Shortage now | No current entry | No current entry |
Source: FDA NDC Directory, CMS NADAC of October 7, 2026 and the FDA Drug Shortage Database (FDA files October 8, 2026)
What next?
- Check more medicines together
- up to five at once