Propranolol · larger labeled portfolio than Dobutamine
SPL labels Dobutamine + Propranolol as minor; Dobutamine 2 / Propranolol 44 in that band.
Mechanism on file: Propranolol blocks the same receptors that dobutamine tries to activate, which stops dobutamine from working correctly. This can also make heart stress tests less accurate because the heart does not respond to the medicine as expected.
FDA SPL severity: Minor
Dobutamine + Propranolol · SPL mechanism field
Propranolol blocks the same receptors that dobutamine tries to activate, which stops dobutamine from working correctly. This can also make heart stress tests less accurate because the heart does not respond to the medicine as expected.
Minor band excerpt · Dobutamine with Propranolol
Isoproterenol and Dobutamine Propranolol is a competitive inhibitor of beta-receptor agonists, and its effects can be reversed by administration of such agents, e.g., dobutamine or isoproterenol. Also, propranolol may reduce sensitivity to dobutamine stress echocardiography in patients undergoing evaluation for myocardial ischemia.
Dobutamine · 2 minor + 3 total pairs
- Atomoxetine minor
- Carbidopa/Levodopa moderate
Propranolol · 44 SPL pairs (broader portfolio than Dobutamine)
- Acetaminophen/Oxycodone minor
- Amiodarone minor
- Celecoxib minor
- Cholestyramine minor
FDA Drug Labels (SPL) via openFDA. Registry display only. Not medical advice.
Read our methodology - how this data is sourced, computed, and verified.