Darunavir · more major-labeled pairs than Dabigatran
SPL labels Dabigatran + Darunavir as minor; Dabigatran 12 / Darunavir 70 in that band.
Mechanism on file: Darunavir blocks a protein that helps remove dabigatran from the body, which can lead to higher levels of the blood thinner in your system.
FDA SPL severity: Minor
Dabigatran + Darunavir · SPL mechanism field
Darunavir blocks a protein that helps remove dabigatran from the body, which can lead to higher levels of the blood thinner in your system.
Minor band excerpt · Dabigatran with Darunavir
dabigatran etexilate edoxaban ↑ dabigatran ↑ edoxaban Refer to the dabigatran etexilate or edoxaban prescribing information for recommendations regarding co-administration. The specific recommendations are based on indication, renal function, and effect of the co-administered P-gp inhibitors on the concentration of dabigatran or edoxaban. Clinical monitoring is recommended when a DOAC not affected by CYP3A4 but transported by P-gp, including dabigatran etexilate and edoxaban, is co-administered with darunavir /ritonavir.
Dabigatran · 12 minor + 15 total pairs
- Amiodarone minor
- Carbamazepine minor
- Clarithromycin minor
- Dronedarone minor
Darunavir · 15 major-labeled pairs (vs Dabigatran's 0)
- Amiodarone minor
- Amitriptyline minor
- Amlodipine minor
- Beclomethasone minor
FDA Drug Labels (SPL) via openFDA. Registry display only. Not medical advice.
Read our methodology - how this data is sourced, computed, and verified.