HIGH-VOLUME · HOSP-MID
ranitidine Side Effects
ranitidine (also sold as Zantac) is HIGH-VOLUME in this FAERS book #28 of 524 by FAERS report count. Signature opener: HOSP-MID - 13.1% mention hospitalization (25,953 reports).
Data updated 2026-05-15
- 197,405
- FAERS reports
FAERS voluntary reports, 1999 to 2025. High volume tracks exposure and reporting culture; see methodology for de-dup rules.
ranitidine: 13.1% mention hospitalization (25,953 reports). Death stamp DEATH-HEAVY; volume band HIGH-VOLUME #28 of 524 by FAERS report count.
High-report extract for ranitidine (Zantac): 197,405 FAERS rows (1999-2025). Top named reactions: BREAST CANCER, PROSTATE CANCER, COLORECTAL CANCER. Outcome stamps DEATH-HEAVY · HOSP-MID · SEX-BALANCED. FAERS is voluntary signal detection, not incidence.
Counts from the openFDA FAERS extract (1999–2025). Stamps MEGA-CASE · DEATH-HEAVY · HOSP-MID · SEX-BALANCED.
BREAST CANCER leads 24,853 of 197,405 reports
Who reports · age peak 45-64 (SEX-BALANCED)
Sex coding · SEX-BALANCED
Age peak 45-64 (43,800 reports)
FAERS filings rising toward 2025
Reactions in Death Reports
Death-mentioned subset is HEAVY here (15,440 reports, 7.8%). Top co-reported reactions in that subset - voluntary, not causal.
| Reaction | Reports |
|---|---|
| DEATH | 2,248 |
| PANCREATIC CARCINOMA | 1,995 |
| HEPATIC CANCER | 1,871 |
| NEOPLASM MALIGNANT | 1,623 |
| OESOPHAGEAL CARCINOMA | 1,456 |
| GASTRIC CANCER | 1,233 |
| LUNG NEOPLASM MALIGNANT | 1,139 |
| COLORECTAL CANCER | 1,013 |
| INCORRECT DOSE ADMINISTERED | 971 |
| BLADDER CANCER | 883 |
| PNEUMONIA | 791 |
| RENAL CANCER | 700 |
| DIARRHOEA | 684 |
| INJURY | 651 |
| FATIGUE | 625 |
| NAUSEA | 613 |
| VOMITING | 608 |
| PAIN | 598 |
| ASTHENIA | 536 |
Reactions in Hospitalization Reports
Hospitalization mid-share (25,953, 13.1%). Co-reported reactions:
| Reaction | Reports |
|---|---|
| NAUSEA | 2,042 |
| DIARRHOEA | 1,967 |
| DYSPNOEA | 1,934 |
| VOMITING | 1,870 |
| PNEUMONIA | 1,740 |
| FATIGUE | 1,719 |
| PAIN | 1,521 |
| PYREXIA | 1,404 |
| ASTHENIA | 1,390 |
| HEADACHE | 1,364 |
| INCORRECT DOSE ADMINISTERED | 1,269 |
| MALAISE | 1,236 |
| DIZZINESS | 1,235 |
| ACUTE KIDNEY INJURY | 1,226 |
| FALL | 1,169 |
| ABDOMINAL PAIN | 1,108 |
| ARTHRALGIA | 1,103 |
| HYPERTENSION | 1,092 |
How to read ranitidine FAERS figures (MEGA-CASE · DEATH-HEAVY · HOSP-MID)
FAERS holds 197,405 voluntary reports linked to ranitidine (Zantac), 1999-2025. Death is listed on 15,440 (7.8%). Hospitalization appears on 25,953 (13.1%). Top co-reported indication: Dyspepsia.
MEGA-CASE books overweight common drugs and loud reporting cultures; HOSP-MID is the page opener, not a per-patient risk.
Read with ranitidine
Peers ranked by ABS(total_reports), then an ABS(death_share) pole; guide hop follows DEATH-HEAVY · HOSP-MID stamps.
ABS(total_reports) peer at 197,074 FAERS cases (Δ 331 lighter vs ranitidine); DEATH-RARE · HOSP-LIGHT · FEMALE-LED vs this page's MEGA-CASE · DEATH-HEAVY · HOSP-MID · SEX-BALANCED.
ABS(total_reports) peer at 196,342 FAERS cases (Δ 1,063 lighter vs ranitidine); DEATH-HEAVY · HOSP-MID · FEMALE-LED vs this page's MEGA-CASE · DEATH-HEAVY · HOSP-MID · SEX-BALANCED.
ABS(total_reports) peer at 194,743 FAERS cases (Δ 2,662 lighter vs ranitidine); DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED vs this page's MEGA-CASE · DEATH-HEAVY · HOSP-MID · SEX-BALANCED.
ABS(total_reports) peer at 200,719 FAERS cases (Δ 3,314 heavier vs ranitidine); DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED vs this page's MEGA-CASE · DEATH-HEAVY · HOSP-MID · SEX-BALANCED.
ABS(death_share) pole at 62.1% death-mentioned reports (Δ 54.3 pp vs ranitidine's DEATH-HEAVY): CASELOAD · HOSP-MID.
ranitidine stamps DEATH-HEAVY · HOSP-MID; FAERS outcome shares are signal-detection rates, not incidence. Read them next to caseload MEGA-CASE and the label guide.