MID-VOLUME · PRODUCT QUALITY ISSUE
methylphenidate Side Effects
methylphenidate (also sold as Ritalin, Concerta) sits MID-VOLUME #201 of 524 by FAERS report count. Lead signal: PRODUCT QUALITY ISSUE - PRODUCT QUALITY ISSUE leads at 5,241 reports (18.8% of the book). Demographics and serious-outcome tables follow.
Data updated 2026-05-15
- 27,931
- FAERS reports
FDA Adverse Event Reporting System extract for methylphenidate. Stamp set CASELOAD · DEATH-MARKED · HOSP-MID. How figures are compiled.
Among 27,931 FAERS reports for methylphenidate, PRODUCT QUALITY ISSUE is the most-reported reaction (5,241). Volume band MID-VOLUME #201 of 524 by FAERS report count.
Mid-book FAERS page for methylphenidate (Ritalin) (27,931 reports). Signature PRODUCT QUALITY ISSUE. Dominant age band on file: 0-17. Educational reference only.
Counts from the openFDA FAERS extract (2004–2025). Stamps CASELOAD · DEATH-MARKED · HOSP-MID · SEX-BALANCED.
PRODUCT QUALITY ISSUE leads 5,241 of 27,931 reports
Who reports · age peak 0-17 (SEX-BALANCED)
Sex coding · SEX-BALANCED
Age peak 0-17 (6,627 reports)
FAERS filings rising toward 2025
Reactions in Death Reports
Death appears on 1,071 reports (3.8% - MARKED). Reactions below co-occur in those rows only.
| Reaction | Reports |
|---|---|
| COMPLETED SUICIDE | 276 |
| TOXICITY TO VARIOUS AGENTS | 273 |
| DEATH | 210 |
| DRUG ABUSE | 164 |
| OVERDOSE | 109 |
| CARDIO-RESPIRATORY ARREST | 107 |
| CARDIAC ARREST | 77 |
| POISONING | 71 |
| DRUG DEPENDENCE | 61 |
| ARTERIOSCLEROSIS CORONARY ARTERY | 52 |
| RESPIRATORY ARREST | 38 |
| UNRESPONSIVE TO STIMULI | 38 |
| INTENTIONAL OVERDOSE | 37 |
| DRUG LEVEL INCREASED | 34 |
| INTENTIONAL PRODUCT MISUSE | 31 |
| PULMONARY OEDEMA | 27 |
| SUSPECTED SUICIDE | 24 |
| FATIGUE | 22 |
| HYPOTENSION | 22 |
Reactions in Hospitalization Reports
Hospitalization mid-share (3,510, 12.6%). Co-reported reactions:
| Reaction | Reports |
|---|---|
| TOXICITY TO VARIOUS AGENTS | 418 |
| AGITATION | 224 |
| TACHYCARDIA | 206 |
| NAUSEA | 188 |
| INTENTIONAL OVERDOSE | 179 |
| VOMITING | 179 |
| ANXIETY | 168 |
| HYPERTENSION | 168 |
| HEADACHE | 162 |
| FATIGUE | 159 |
| DRUG INTERACTION | 158 |
| OVERDOSE | 155 |
| DRUG ABUSE | 149 |
| SUICIDE ATTEMPT | 142 |
| DIZZINESS | 130 |
| INSOMNIA | 127 |
| CONFUSIONAL STATE | 125 |
| CONDITION AGGRAVATED | 124 |
How to read methylphenidate FAERS figures (CASELOAD · DEATH-MARKED · HOSP-MID)
FAERS holds 27,931 voluntary reports linked to methylphenidate (Ritalin, Concerta), 2004-2025. Death is listed on 1,071 (3.8%). Hospitalization appears on 3,510 (12.6%). Top co-reported indication: Attention Deficit/Hyperactivity Disorder.
Mid-volume extract - treat DEATH-MARKED · HOSP-MID as signal-detection rates next to PRODUCT QUALITY ISSUE leads at 5,241 reports (18.8% of the book).
Read with methylphenidate
Peers ranked by ABS(total_reports), then an ABS(death_share) pole; guide hop follows DEATH-MARKED · HOSP-MID stamps.
ABS(total_reports) peer at 28,005 FAERS cases (Δ 74 heavier vs methylphenidate); DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED vs this page's CASELOAD · DEATH-MARKED · HOSP-MID · SEX-BALANCED.
ABS(total_reports) peer at 28,128 FAERS cases (Δ 197 heavier vs methylphenidate); DEATH-MARKED · HOSP-MID · FEMALE-LED vs this page's CASELOAD · DEATH-MARKED · HOSP-MID · SEX-BALANCED.
ABS(total_reports) peer at 27,449 FAERS cases (Δ 482 lighter vs methylphenidate); DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED vs this page's CASELOAD · DEATH-MARKED · HOSP-MID · SEX-BALANCED.
ABS(total_reports) peer at 28,434 FAERS cases (Δ 503 heavier vs methylphenidate); DEATH-HEAVY · HOSP-MID · FEMALE-LED vs this page's CASELOAD · DEATH-MARKED · HOSP-MID · SEX-BALANCED.
ABS(death_share) pole at 62.1% death-mentioned reports (Δ 58.3 pp vs methylphenidate's DEATH-MARKED): CASELOAD · HOSP-MID.
methylphenidate sits in CASELOAD; high report volume tracks exposure and reporting culture more than per-patient risk. Methodology states the de-dup rules.