MID-VOLUME · HOSP-HEAVY

isosorbide dinitrate Side Effects

isosorbide dinitrate (also sold as Isordil) sits MID-VOLUME #241 of 524 by FAERS report count. Lead signal: HOSP-HEAVY - 42.9% mention hospitalization (8,172 reports). Demographics and serious-outcome tables follow.

Data updated 2026-05-15

19,058
FAERS reports

FDA Adverse Event Reporting System extract for isosorbide dinitrate. Stamp set WATCHLIST · DEATH-HEAVY · HOSP-HEAVY. How figures are compiled.

isosorbide dinitrate: 42.9% mention hospitalization (8,172 reports). Death stamp DEATH-HEAVY; volume band MID-VOLUME #241 of 524 by FAERS report count.

Mid-book FAERS page for isosorbide dinitrate (Isordil) (19,058 reports). Signature HOSP-HEAVY. Dominant age band on file: 75+. Educational reference only.

Counts from the openFDA FAERS extract (1996–2025). Stamps WATCHLIST · DEATH-HEAVY · HOSP-HEAVY · SEX-BALANCED.

DYSPNOEA leads 1,608 of 19,058 reports

DYSPNOEA
1,608
NAUSEA
1,317
FATIGUE
1,302
DIZZINESS
1,265
DIARRHOEA
1,248
MYOCARDIAL INFARCTION
1,179
CHEST PAIN
1,118
PAIN
1,023
HEADACHE
970
VOMITING
961
MALAISE
866
ASTHENIA
799
DEATH
787
ARTHRALGIA
765
PRURITUS
760
RENAL FAILURE
760
PYREXIA
707
ANXIETY
702

Who reports · age peak 75+ (SEX-BALANCED)

Sex coding · SEX-BALANCED

Female 8,456 (47%)
Male 9,439 (53%)
Unknown 20

Age peak 75+ (5,434 reports)

0-17 62 (0%)
18-44 393 (3%)
45-64 3,373 (26%)
65-74 3,604 (28%)
75+ 5,434 (42%)

FAERS filings rising toward 2025

1996 2025

Reactions in Death Reports

Death-mentioned subset is HEAVY here (2,531 reports, 13.3%). Top co-reported reactions in that subset - voluntary, not causal.

Reaction Reports
DEATH 784
RENAL FAILURE 224
CARDIAC FAILURE CONGESTIVE 205
PNEUMONIA 198
MYOCARDIAL INFARCTION 173
DYSPNOEA 167
CARDIAC ARREST 138
ACUTE KIDNEY INJURY 129
CARDIAC FAILURE 127
CHRONIC KIDNEY DISEASE 120
ASTHENIA 116
NAUSEA 112
RESPIRATORY FAILURE 109
HYPOTENSION 104
PAIN 101
DIARRHOEA 99
CARDIO-RESPIRATORY ARREST 97
ANAEMIA 96
ATRIAL FIBRILLATION 95
COMPLETED SUICIDE 95

Reactions in Hospitalization Reports

Hospitalization is HEAVY (8,172, 42.9% of the book). Top reactions in those rows:

Reaction Reports
DYSPNOEA 804
MYOCARDIAL INFARCTION 713
CHEST PAIN 619
CARDIAC FAILURE CONGESTIVE 563
NAUSEA 557
DIZZINESS 553
PNEUMONIA 553
DIARRHOEA 486
FATIGUE 481
VOMITING 470
ASTHENIA 449
FALL 446
RENAL FAILURE 414
HYPOTENSION 412
PAIN 394
PYREXIA 364
ACUTE KIDNEY INJURY 363
MALAISE 363
DEHYDRATION 347
ANAEMIA 346
How to read isosorbide dinitrate FAERS figures (WATCHLIST · DEATH-HEAVY · HOSP-HEAVY)

FAERS holds 19,058 voluntary reports linked to isosorbide dinitrate (Isordil), 1996-2025. Death is listed on 2,531 (13.3%). Hospitalization appears on 8,172 (42.9%). Top co-reported indication: Product Used For Unknown Indication.

Mid-volume extract - treat DEATH-HEAVY · HOSP-HEAVY as signal-detection rates next to 42.9% mention hospitalization (8,172 reports).

Read with isosorbide dinitrate

Peers ranked by ABS(total_reports), then an ABS(death_share) pole; guide hop follows DEATH-HEAVY · HOSP-HEAVY stamps.