PlainMeds provides educational information only. This is not medical advice. Always consult your doctor or pharmacist.

dopamine Side Effects

Also known as: Intropin

Analysis of 2,938 adverse event reports submitted to the FDA from 1997 to 2025.

Total Reports

2,938

Death-Related

976

33.2% of reports

Hospitalizations

1,540

52.4% of reports

Top Indication

Product Used For Unknown Indication

Most Reported Adverse Reactions

DRUG INEFFECTIVE
549
HYPOTENSION
336
OFF LABEL USE
248
ACUTE KIDNEY INJURY
182
CARDIAC ARREST
165
RENAL FAILURE
162
CONDITION AGGRAVATED
125
DEATH
125
TOXICITY TO VARIOUS AGENTS
124
SEPSIS
113
BRADYCARDIA
112
DYSPNOEA
112
DIARRHOEA
104
RESPIRATORY FAILURE
104
PNEUMONIA
100
DRUG INTERACTION
99
METABOLIC ACIDOSIS
96
PYREXIA
96
CARDIOGENIC SHOCK
94
PAIN
93

Who Reports Side Effects

Gender Distribution

Female 1,249 (48%)
Male 1,373 (52%)
Unknown 4

Age Distribution

0-17 452 (20%)
18-44 494 (22%)
45-64 602 (27%)
65-74 368 (17%)
75+ 292 (13%)

Reporting Trend by Year

1997 2025

Reactions in Death Reports

Top reactions reported in 976 reports where death was an outcome. These are voluntarily reported and do not establish causation.

Reaction Reports
DRUG INEFFECTIVE 212
HYPOTENSION 145
DEATH 125
CARDIAC ARREST 99
RENAL FAILURE 85
SEPSIS 81
OFF LABEL USE 75
RESPIRATORY FAILURE 66
MULTIPLE ORGAN DYSFUNCTION SYNDROME 64
ACUTE KIDNEY INJURY 57
PNEUMONIA 57
MULTI-ORGAN FAILURE 53
CONDITION AGGRAVATED 52
SEPTIC SHOCK 50
DYSPNOEA 47
BRADYCARDIA 46
CARDIAC FAILURE 45
PAIN 45
TOXICITY TO VARIOUS AGENTS 44
INJURY 43

Reactions in Hospitalization Reports

Top reactions in 1,540 reports where hospitalization was an outcome.

Reaction Reports
DRUG INEFFECTIVE 338
HYPOTENSION 219
OFF LABEL USE 130
ACUTE KIDNEY INJURY 128
CARDIAC ARREST 98
TOXICITY TO VARIOUS AGENTS 97
RENAL FAILURE 92
DIARRHOEA 85
BRADYCARDIA 78
DRUG INTERACTION 77
DYSPNOEA 76
PNEUMONIA 73
SEPSIS 70
PYREXIA 69
SHOCK 68
RESPIRATORY FAILURE 67
METABOLIC ACIDOSIS 65
CARDIOGENIC SHOCK 63
CARDIAC FAILURE 62
CONDITION AGGRAVATED 62

Nearby — Related Medications

Compare dopamine vs adenosine →

What the FAERS Data Reveals About dopamine Side Effects

The FDA Adverse Event Reporting System (FAERS) contains 2,938 voluntary reports linked to dopamine and its brand equivalents (Intropin), spanning 1997 through 2025. Of those, 976 (33.2%) listed death as an outcome and 1,540 (52.4%) involved hospitalization. The most common indication reported alongside adverse events was Product Used For Unknown Indication.

Demographic breakdowns help contextualize who is being exposed to the drug. Of reports with known sex, 48% were female and 52% male; age distribution skews toward 45-64, with 602 reports in that bracket. The single most reported reaction is drug ineffective with 549 submissions, followed by hypotension and off label use.

FAERS is a signal-detection tool, not a scorecard. Reports are voluntary, and a single case may list multiple suspect drugs, so numbers above should not be read as incidence rates or per-patient risk. Widely prescribed drugs naturally accumulate more reports than niche therapies even when individual risk is low. These aggregates are useful for spotting patterns that merit further pharmacovigilance, not for choosing between medications. This page is for educational reference only and is not medical advice — speak with a licensed clinician about any side-effect concerns.