spironolactone vs spironolactone (acne)
Side-by-side comparison of spironolactone and spironolactone (acne). Data from FDA drug databases (Orange Book, NDC Directory, recalls, shortages) covering 20,000+ approved drugs, plus CMS pricing; see our methodology.
minor Known Drug Interaction
• NSAIDs: May reduce the diuretic, natriuretic and antihypertensive effect of ALDACTONE ( 7.3 ). • Digoxin: ALDACTONE can interfere with radioimmunologic assays of digoxin exposure ( 7.4 ). • Acetylsalicylic Acid (ASA): ASA may reduce the efficacy of ALDACTONE ( 7.6 ).
Recommendation: Ask your doctor before taking any over-the-counter pain medicine while on this treatment.
Aldactone
Aldactone
Spironolactone is a medicine that helps remove extra fluid from your body and lower blood pressure. It also helps your heart work better if you have heart failure.
Spironolactone (Aldactone) is a medicine that helps remove extra fluid from your body and lower blood pressure. It belongs to a class of drugs called anti-androgens.
Spironolactone is used to treat heart failure by reducing fluid build-up and helping you live longer. It also treats high blood pressure, which can lower your chance of having a stroke or heart attack. This medicine can also manage fluid build-up caused by liver problems or a kidney problem called nephrotic syndrome. It can also treat a condition where your body makes too much of a hormone called aldosterone.
Spironolactone can treat heart failure by helping you live longer, managing swelling, and reducing hospital visits. It also treats high blood pressure, which lowers the risk of strokes and heart attacks. This medicine can also manage swelling caused by liver problems or a kidney problem called nephrotic syndrome when other treatments don't work well enough. It can also treat primary hyperaldosteronism, a condition where your body makes too much aldosterone.
Spironolactone belongs to a class of drugs called aldosterone antagonists. It works by blocking the effects of aldosterone, a hormone that causes your body to hold onto salt and water. By blocking aldosterone, spironolactone helps your body get rid of extra fluid and salt, which lowers blood pressure and reduces strain on the heart.
Spironolactone blocks a hormone called aldosterone in your body. Aldosterone causes your body to hold onto sodium and water. By blocking aldosterone, spironolactone helps your body get rid of extra fluid and lower blood pressure.
- • Breast enlargement in men
- • Dizziness
- • Headache
- • Breast enlargement in men
- • Changes in periods
- • Decreased sex drive
- • Dizziness
- • Headache
- Difficulty breathing 10,389
- Tiredness 8,179
- Feeling sick to your stomach 7,818
- Loose stools 7,416
- Sudden kidney damage 6,785
No adverse event reports.
Spironolactone can cause your potassium levels to get too high, which can be dangerous. Your doctor will check your potassium levels regularly, especially if you have kidney problems or are taking other medicines that can raise potassium. This medicine can also cause low blood pressure or make kidney problems worse. Tell your doctor if you have side effects.
Spironolactone can cause high potassium levels in your blood. Your doctor will check your potassium levels regularly, especially if you have kidney problems or take other medicines that can raise potassium. This medicine can also cause low blood pressure or make kidney problems worse. Tell your doctor if you have liver problems, as this medicine can cause problems with brain function.
Spironolactone may affect the sex organs of a baby boy if taken during pregnancy. Talk to your doctor if you are pregnant or plan to become pregnant. It is not known if spironolactone passes into breast milk, so talk to your doctor about the best way to feed your baby if you are taking this medicine.
Spironolactone may affect the sex organs of a baby boy if taken during pregnancy. Talk to your doctor about the risks if you are pregnant or plan to become pregnant. It is not known if spironolactone passes into breast milk, so talk to your doctor about breastfeeding while taking this medicine.
How to Read This spironolactone vs spironolactone (acne) Comparison
spironolactone is classified in the Potassium-Sparing Diuretic / Aldosterone Antagonist drug class, while spironolactone (acne) sits within the Anti-Androgen class. Drugs from different classes work through distinct mechanisms, so a head-to-head comparison illustrates trade-offs rather than equivalence. Both drugs are prescription-only, so a licensed provider must authorize use.
Adverse event totals above are pulled from the FDA's Adverse Event Reporting System (FAERS). For these top-ranked reactions alone, spironolactone has 40,587 submissions while spironolactone (acne) has 0. Those figures reflect cumulative reporting volume, not per-patient risk, so older, widely dispensed drugs typically look worse on count alone. These two drugs have a known minor interaction flagged in FDA labeling, attributed to pain relievers like aspirin or ibuprofen can stop this medicine from working well to lower blood pressure or remove extra fluid.. Serious warnings, pregnancy guidance, and contraindications can differ even when indications overlap.
A table cannot substitute for clinical judgment. Effectiveness, tolerability, drug-drug interactions with your other medications, kidney and liver function, pregnancy status, insurance formulary, and price all feed into a decision that only a licensed prescriber can make responsibly. Data here is sourced from FDA Structured Product Labels (SPL) and FAERS, both of which update as manufacturers and clinicians submit new information. This page is for educational purposes only, is not medical advice, and should not be used to self-switch between spironolactone and spironolactone (acne) - always consult your physician or pharmacist first.
Important: This comparison is for informational purposes only. Drug effects vary between individuals. Always consult your doctor or pharmacist for personalized medical advice.