omeprazole vs tolterodine
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Side-by-side comparison of omeprazole and tolterodine. Data from FDA drug databases (Orange Book, NDC Directory, recalls, shortages) covering 20,000+ approved drugs, plus CMS pricing; see our methodology.
minor Known Drug Interaction
7.4 Other Drugs Metabolized by Cytochrome P450 Isoenzymes In vivo drug-interaction data show that tolterodine immediate release does not result in clinically relevant inhibition of CYP1A2, 2D6, 2C9, 2C19, or 3A4 as evidenced by lack of influence on the marker drugs caffeine, debrisoquine, S-warfarin, and omeprazole [see Clinical Pharmacology (12.3) ] . In vivo drug-interaction data show that tolterodine immediate release does not result in clinically relevant inhibition of CYP1A2, 2D6, 2C9, 2C19, or 3A4 as evidenced by lack of influence on the marker drugs caffeine, debrisoquine,...
Prilosec
Detrol
Omeprazole (Prilosec) is a medicine that reduces the amount of acid in your stomach. It belongs to a class of drugs called proton pump inhibitors (PPIs).
Tolterodine extended-release capsules help control an overactive bladder. It reduces the feeling of needing to go to the bathroom often.
This medicine treats frequent heartburn, which is heartburn that occurs 2 or more days a week. It is not meant to give you immediate relief from heartburn. It may take 1 to 4 days for the medicine to fully work.
This medicine treats overactive bladder. It helps reduce leaking urine, the strong need to urinate, and frequent urination. These symptoms are also known as urge urinary incontinence, urgency, and frequency.
Omeprazole works by blocking the production of acid in your stomach. It does this by targeting the cells that make stomach acid. This helps to reduce heartburn symptoms.
Tolterodine belongs to a class of drugs called antimuscarinics. It works by blocking certain nerve signals to the bladder. This helps to relax the bladder muscles and reduce the urge to urinate.
- • Headache
- • Dry mouth
- • Headache
- • Constipation
- • Abdominal pain
- Fatigue 19,901
- Nausea 19,842
- Diarrhoea 19,627
- Dyspnoea 16,336
- Headache 14,629
- Fall 408
- Fatigue 406
- Dizziness 309
- Diarrhoea 308
- Nausea 308
Children under 18 should ask a doctor before use. Heartburn in children may be a sign of a serious condition.
Anaphylaxis and angioedema (severe allergic reactions) have happened with this drug. These reactions can cause difficulty breathing and require emergency treatment. Use caution if you have bladder problems, gastrointestinal issues, or glaucoma. This medicine can cause sleepiness, so be careful driving or operating heavy machinery.
Talk to your doctor if you are pregnant or breastfeeding before taking this medicine. It is important to weigh the benefits and risks with your doctor.
It is not known if tolterodine is safe to use during pregnancy. Talk to your doctor if you are pregnant or plan to become pregnant. It is also not known if tolterodine passes into breast milk. Talk to your doctor about the best way to feed your baby if you are taking this medicine.
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How to Read This omeprazole vs tolterodine Comparison
omeprazole is classified in the Proton Pump Inhibitor (PPI) drug class, while tolterodine sits within the Anticholinergic (Overactive Bladder) class. Drugs from different classes work through distinct mechanisms, so a head-to-head comparison illustrates trade-offs rather than equivalence. Both drugs are split between OTC and prescription status, which affects access and supervision.
Adverse event totals above are pulled from the FDA's Adverse Event Reporting System (FAERS). For these top-ranked reactions alone, omeprazole has 90,335 submissions while tolterodine has 1,739. Those figures reflect cumulative reporting volume, not per-patient risk, so older, widely dispensed drugs typically look worse on count alone. These two drugs have a known minor interaction flagged in FDA labeling, attributed to tolterodine does not change how the body processes omeprazole, meaning they do not have a meaningful interaction.. Serious warnings, pregnancy guidance, and contraindications can differ even when indications overlap.
A table cannot represent individual circumstances. Data here is sourced from FDA Structured Product Labels (SPL) and FAERS, both of which update as manufacturers and clinicians submit new information. This registry does not provide medical, treatment, substitution, or medication-change directions for omeprazole or tolterodine.
Registry boundary: This comparison displays source-record fields and does not provide individualized medical direction.