moxifloxacin vs pimozide
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Side-by-side comparison of moxifloxacin and pimozide. Data from FDA drug databases (Orange Book, NDC Directory, recalls, shortages) covering 20,000+ approved drugs, plus CMS pricing; see our methodology.
minor Known Drug Interaction
Accordingly, pimozide should not be given with dofetilide, sotalol, quinidine, other Class Ia and III anti-arrhythmics, mesoridazine, thioridazine, chlorpromazine, droperidol, sparfloxacin, gatifloxacin, moxifloxacin, halofantrine, mefloquine, pentamidine, arsenic trioxide, levomethadyl acetate, dolasetron mesylate, probucol, tacrolimus, ziprasidone, or other drugs that have demonstrated QT prolongation as one of their pharmacodynamic effects.
Avelox
Orap
Moxifloxacin is an antibiotic that fights bacteria in your body. It is used to treat different types of infections.
Pimozide (Orap) is a medicine that helps control tics in people with Tourette's Disorder. It works by affecting certain chemicals in the brain.
Moxifloxacin treats infections like pneumonia, skin infections, and infections in your stomach area. It can also treat sinus infections, bronchitis, and plague. This medicine should only be used to treat infections that are proven or very likely to be caused by bacteria that it can kill.
Pimozide is used to treat motor and phonic tics in people with Tourette's Disorder. It is for people who have not had success with other treatments. This medicine is not for tics that are mild or just annoying. It is meant for people whose tics greatly affect their daily life.
Moxifloxacin belongs to a class of drugs called fluoroquinolones. It works by stopping bacteria from multiplying. This helps your body fight off the infection.
Pimozide belongs to a class of drugs called antipsychotics. It works by blocking dopamine, a chemical in the brain. By blocking dopamine, pimozide helps to reduce tics.
- • Nausea
- • Diarrhea
- • Headache
- • Dizziness
- • Parkinson-like symptoms (tremors, stiffness)
- • Restlessness
- • Muscle stiffness
- • Drowsiness
- Dyspnoea 1,225
- Pneumonia 1,142
- Vomiting 1,101
- Drug Hypersensitivity 1,073
- Asthma 910
- Drug Interaction 76
- Parkinsonism 42
- Weight Increased 37
- Somnolence 33
- Hypotension 29
Moxifloxacin can cause serious side effects, even if they don't happen to everyone. These include tendon problems, nerve damage, and central nervous system problems. If you have myasthenia gravis, moxifloxacin can make your muscle weakness worse. If you experience any of these serious side effects, stop taking moxifloxacin immediately and talk to your doctor. Because of these risks, moxifloxacin should only be used when other treatment options are not available for sinus infections or bronchitis.
Pimozide can cause changes in your heart rhythm (QT prolongation). This can lead to serious heart problems. You should have an ECG (heart test) before starting pimozide and regularly during treatment. Do not take pimozide with other medicines that can also affect your heart rhythm.
Talk to your doctor if you are pregnant or plan to become pregnant. Moxifloxacin may harm your unborn baby. It is not known if moxifloxacin passes into breast milk, so talk to your doctor if you are breastfeeding.
Tell your doctor if you are pregnant or plan to become pregnant. It is not known if pimozide will harm your unborn baby. Talk to your doctor about the risks and benefits of taking pimozide during pregnancy and breastfeeding.
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How to Read This moxifloxacin vs pimozide Comparison
moxifloxacin is classified in the Fluoroquinolone Antibiotic drug class, while pimozide sits within the Typical Antipsychotic class. Drugs from different classes work through distinct mechanisms, so a head-to-head comparison illustrates trade-offs rather than equivalence. Both drugs are prescription-only, so a licensed provider must authorize use.
Adverse event totals above are pulled from the FDA's Adverse Event Reporting System (FAERS). For these top-ranked reactions alone, moxifloxacin has 5,451 submissions while pimozide has 217. Those figures reflect cumulative reporting volume, not per-patient risk, so older, widely dispensed drugs typically look worse on count alone. These two drugs have a known minor interaction flagged in FDA labeling, attributed to both drugs can cause a change in the heart's electrical rhythm. taking them together increases the risk of a dangerous heartbeat.. Serious warnings, pregnancy guidance, and contraindications can differ even when indications overlap.
A table cannot represent individual circumstances. Data here is sourced from FDA Structured Product Labels (SPL) and FAERS, both of which update as manufacturers and clinicians submit new information. This registry does not provide medical, treatment, substitution, or medication-change directions for moxifloxacin or pimozide.
Registry boundary: This comparison displays source-record fields and does not provide individualized medical direction.