metoclopramide vs rasagiline
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Side-by-side comparison of metoclopramide and rasagiline. Data from FDA drug databases (Orange Book, NDC Directory, recalls, shortages) covering 20,000+ approved drugs, plus CMS pricing; see our methodology.
minor Known Drug Interaction
7.8 Dopaminergic Antagonists It is possible that dopamine antagonists, such as antipsychotics or metoclopramide, could diminish the effectiveness of rasagiline.
Reglan
Azilect
Metoclopramide is a drug that helps with stomach problems. It can help food move faster through your stomach and reduce nausea.
Rasagiline (Azilect) is a medicine used to treat Parkinson's disease. It helps to improve motor control and reduce symptoms like tremors and stiffness.
This medicine treats heartburn caused by acid reflux when other treatments don't work. It also helps with symptoms of slow stomach emptying in people with diabetes, like nausea, vomiting, and feeling full. This medicine is for adults and should not be used for more than 12 weeks.
Rasagiline is used to treat Parkinson's disease. Parkinson's disease is a brain disorder that affects movement. This medicine can be used alone or with other Parkinson's medicines to help control your symptoms.
Metoclopramide helps your stomach muscles move faster. This helps food empty from your stomach more quickly. It also blocks a chemical in your brain that causes nausea.
Rasagiline belongs to a class of drugs called MAO-B inhibitors. It works by increasing the levels of certain chemicals in the brain. These chemicals help to control movement and reduce Parkinson's symptoms.
- • Restlessness
- • Drowsiness
- • Fatigue
- • Feeling tired
- • Flu-like symptoms
- • Joint pain
- • Depression
- • Indigestion
- • Swelling in the arms or legs
- Tardive Dyskinesia 13,205
- Extrapyramidal Disorder 11,628
- Nervous System Disorder 7,175
- Dystonia 6,661
- Pain 4,666
- Fall 343
- Hallucination 326
- Dyskinesia 276
- Parkinson^S Disease 216
- Dizziness 205
Metoclopramide can cause a serious movement disorder called tardive dyskinesia. This may not go away even after you stop taking the medicine. The risk of tardive dyskinesia increases with long-term use and high doses. Call your doctor right away if you have uncontrolled muscle movements.
Rasagiline can cause high blood pressure. It can also cause serotonin syndrome, a serious condition, especially when taken with antidepressants. You may fall asleep suddenly or feel very drowsy. Rasagiline can also cause or worsen uncontrolled movements, hallucinations, and compulsive behaviors. Tell your doctor if you experience any of these side effects.
Tell your doctor if you are pregnant or plan to become pregnant. It is not known if this medicine will harm your unborn baby. Talk to your doctor about the risks and benefits of taking this medicine while breastfeeding.
It is not known if rasagiline can harm an unborn baby. Talk to your doctor if you are pregnant or plan to become pregnant. It is also not known if rasagiline passes into breast milk, so talk to your doctor if you are breastfeeding.
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How to Read This metoclopramide vs rasagiline Comparison
metoclopramide is classified in the Prokinetic / Antiemetic drug class, while rasagiline sits within the MAO-B Inhibitor class. Drugs from different classes work through distinct mechanisms, so a head-to-head comparison illustrates trade-offs rather than equivalence. Both drugs are prescription-only, so a licensed provider must authorize use.
Adverse event totals above are pulled from the FDA's Adverse Event Reporting System (FAERS). For these top-ranked reactions alone, metoclopramide has 43,335 submissions while rasagiline has 1,366. Those figures reflect cumulative reporting volume, not per-patient risk, so older, widely dispensed drugs typically look worse on count alone. These two drugs have a known minor interaction flagged in FDA labeling, attributed to metoclopramide blocks the effects of dopamine, which is the opposite of how rasagiline works. this can make rasagiline less effective at treating your condition.. Serious warnings, pregnancy guidance, and contraindications can differ even when indications overlap.
A table cannot represent individual circumstances. Data here is sourced from FDA Structured Product Labels (SPL) and FAERS, both of which update as manufacturers and clinicians submit new information. This registry does not provide medical, treatment, substitution, or medication-change directions for metoclopramide or rasagiline.
Registry boundary: This comparison displays source-record fields and does not provide individualized medical direction.