ketoconazole vs salmeterol

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Side-by-side comparison of ketoconazole and salmeterol. Data from FDA drug databases (Orange Book, NDC Directory, recalls, shortages) covering 20,000+ approved drugs, plus CMS pricing; see our methodology.

moderate Known Drug Interaction

Avoid strong cytochrome P450 3A4 inhibitors (e.g., ritonavir, ketoconazole): May increase risk of systemic corticosteroid and cardiovascular effects. The use of strong CYP3A4 inhibitors (e.g., ritonavir, atazanavir, clarithromycin, indinavir, itraconazole, nefazodone, nelfinavir, saquinavir, ketoconazole, telithromycin) with Fluticasone Propionate/Salmeterol MDPI is not recommended because increased systemic corticosteroid and increased cardiovascular adverse effects may occur. Ketoconazole : Fluticasone Propionate: Coadministration of orally inhaled fluticasone propionate (1,000 mcg) and...

Drug Class
ketoconazole Azole Antifungal
salmeterol Long-Acting Beta-2 Agonist (LABA)
Type
ketoconazole Over-the-Counter
salmeterol Prescription
Summary
ketoconazole

Ketoconazole shampoo is an antifungal medicine. It treats a fungal infection on your skin.

salmeterol

No summary available.

What It Treats
ketoconazole

This shampoo treats tinea versicolor, a fungal infection. This infection can cause patches on your skin that are lighter or darker than the surrounding skin. These patches may appear on your trunk, neck, arms, and upper thighs.

salmeterol

Information not available.

How It Works
ketoconazole

Ketoconazole is an antifungal medicine. It works by stopping the growth of the fungus. This helps to clear up the infection.

salmeterol

Information not available.

Common Side Effects
ketoconazole

No common side effects listed.

salmeterol
  • Nasopharyngitis (common cold)
  • Oral candidiasis (thrush)
  • Headache
  • Cough
  • Back pain
FAERS Reports
ketoconazole
  • Fatigue 929
  • Pruritus 902
  • Nausea 834
  • Rash 802
  • Diarrhoea 760
salmeterol

No adverse event reports.

Serious Warnings
ketoconazole

You should not use this shampoo if you are allergic to ketoconazole or any of the other ingredients.

salmeterol

No specific warnings noted.

Pregnancy
ketoconazole

It is not known if ketoconazole shampoo can harm an unborn baby. Talk to your doctor if you are pregnant or breastfeeding before using this medicine.

salmeterol

No pregnancy information available.

Also Compare, Nearby Drugs

How to Read This ketoconazole vs salmeterol Comparison

ketoconazole is classified in the Azole Antifungal drug class, while salmeterol sits within the Long-Acting Beta-2 Agonist (LABA) class. Drugs from different classes work through distinct mechanisms, so a head-to-head comparison illustrates trade-offs rather than equivalence. Both drugs are split between OTC and prescription status, which affects access and supervision.

Adverse event totals above are pulled from the FDA's Adverse Event Reporting System (FAERS). For these top-ranked reactions alone, ketoconazole has 4,227 submissions while salmeterol has 0. Those figures reflect cumulative reporting volume, not per-patient risk, so older, widely dispensed drugs typically look worse on count alone. These two drugs have a known moderate interaction flagged in FDA labeling, attributed to ketoconazole stops your body from breaking down salmeterol, which can cause the drug to build up in your blood. this increase can lead to heart issues and other side effects throughout your body.. Serious warnings, pregnancy guidance, and contraindications can differ even when indications overlap.

A table cannot represent individual circumstances. Data here is sourced from FDA Structured Product Labels (SPL) and FAERS, both of which update as manufacturers and clinicians submit new information. This registry does not provide medical, treatment, substitution, or medication-change directions for ketoconazole or salmeterol.

Registry boundary: This comparison displays source-record fields and does not provide individualized medical direction.