insulin human/insulin isophane vs lithium
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Side-by-side comparison of insulin human/insulin isophane and lithium. Data from FDA drug databases (Orange Book, NDC Directory, recalls, shortages) covering 20,000+ approved drugs, plus CMS pricing; see our methodology.
minor Known Drug Interaction
Drugs that May Increase or Decrease the Blood Glucose Lowering Effect of HUMULIN 70/30 Drugs: Alcohol, beta-blockers, clonidine, and lithium salts.
Humulin 70/30
Lithobid, Eskalith
Humulin 70/30 is a mix of two types of insulin. It helps control blood sugar in adults with diabetes.
Lithium is a mood stabilizer medicine. It helps to balance mood swings.
Humulin 70/30 is used to improve blood sugar control in adults with diabetes. Diabetes is a condition where your body does not make enough insulin or cannot use insulin properly. This medicine helps your body use sugar from the food you eat for energy.
Lithium is used to treat bipolar disorder. Bipolar disorder causes unusual shifts in mood, energy, activity levels, and concentration. Lithium helps to control the extreme highs (mania) and lows (depression) of this condition.
This medicine is a mix of two insulins: one that works quickly and one that works longer. The short-acting insulin helps control blood sugar after meals. The intermediate-acting insulin works between meals and during the night.
Lithium affects the flow of sodium in nerve and muscle cells in the body. This helps to stabilize your mood. It may also affect other chemical messenger systems in the brain.
- • Low blood sugar (hypoglycemia)
- • Allergic reactions like redness and swelling at the injection site
- • Skin changes at the injection site
- • Weight gain
- • Tremor (shaking)
- • Nausea
- • Increased weight
- • Fatigue (feeling tired)
- • Vomiting
- High blood sugar 10,557
- Low blood sugar 3,451
- Wrong dose given 2,164
- Low blood sugar 1,532
- Feeling sick to your stomach 1,473
- Toxicity To Various Agents 2,179
- Drug Interaction 1,526
- Tremor 1,462
- Nausea 1,344
- Weight Increased 1,153
Never share a Humulin 70/30 KwikPen or syringe with anyone else, even if the needle is changed. Sharing pens or syringes can spread blood-borne diseases. Changes in your insulin dose should be done carefully with your doctor's supervision. Low blood sugar can be life-threatening. Fluid retention and heart failure can occur if you also take thiazolidinediones (TZDs).
Lithium levels in your blood need to be monitored closely by your doctor. Too much lithium can be toxic and cause serious side effects. Make sure to attend all scheduled blood tests.
Tell your doctor if you are pregnant or plan to become pregnant. Good control of diabetes is important during pregnancy. This medicine may pass into breast milk, but it is not expected to harm your baby.
Lithium can harm your unborn baby. Talk to your doctor if you are pregnant or plan to become pregnant. Lithium can pass into breast milk and may harm a nursing infant. Talk to your doctor about the best way to feed your baby if you are taking lithium.
How to Read This insulin human/insulin isophane vs lithium Comparison
insulin human/insulin isophane is classified in the Intermediate-Acting Insulin Combination drug class, while lithium sits within the Mood Stabilizer class. Drugs from different classes work through distinct mechanisms, so a head-to-head comparison illustrates trade-offs rather than equivalence. Both drugs are prescription-only, so a licensed provider must authorize use.
Adverse event totals above are pulled from the FDA's Adverse Event Reporting System (FAERS). For these top-ranked reactions alone, insulin human/insulin isophane has 19,177 submissions while lithium has 7,664. Those figures reflect cumulative reporting volume, not per-patient risk, so older, widely dispensed drugs typically look worse on count alone. These two drugs have a known minor interaction flagged in FDA labeling, attributed to lithium can cause your blood sugar to go up or down unpredictably when used with insulin.. Serious warnings, pregnancy guidance, and contraindications can differ even when indications overlap.
A table cannot represent individual circumstances. Data here is sourced from FDA Structured Product Labels (SPL) and FAERS, both of which update as manufacturers and clinicians submit new information. This registry does not provide medical, treatment, substitution, or medication-change directions for insulin human/insulin isophane or lithium.
Registry boundary: This comparison displays source-record fields and does not provide individualized medical direction.