glucagon vs indomethacin

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Side-by-side comparison of glucagon and indomethacin. Data from FDA drug databases (Orange Book, NDC Directory, recalls, shortages) covering 20,000+ approved drugs, plus CMS pricing; see our methodology.

minor Known Drug Interaction

Indomethacin Clinical Impact: In patients taking indomethacin, Glucagon for Injection may lose its ability to raise blood glucose or may even produce hypoglycemia. Intervention: Monitor blood glucose levels during glucagon treatment of patients taking indomethacin. ( 7 ) • Indomethacin : In patients taking indomethacin Glucagon for Injection may lose its ability to raise glucose or may produce hypoglycemia.

Drug Class
glucagon Glucagon (Hypoglycemia Rescue)
indomethacin Nonsteroidal Anti-Inflammatory Drug (NSAID)
Type
glucagon Prescription
indomethacin Prescription
Summary
glucagon

Glucagon is a medicine that helps raise your blood sugar if it gets too low. It can also be used to temporarily slow down your digestive system for certain medical tests.

indomethacin

Indomethacin is a drug that reduces pain and swelling. It belongs to a class of drugs called NSAIDs.

What It Treats
glucagon

Glucagon is used to treat very low blood sugar in adults and children who have diabetes. It can also be used to help with some X-ray tests in adults. It does this by slowing down the movement of your stomach and intestines.

indomethacin

Indomethacin treats moderate to severe rheumatoid arthritis, ankylosing spondylitis, and osteoarthritis. It can also help with acute painful shoulder (bursitis or tendinitis) and gouty arthritis. This medicine reduces pain and swelling in your joints.

How It Works
glucagon

Glucagon works by telling your liver to release stored sugar into your blood. This raises your blood sugar level quickly. It also relaxes the muscles in your stomach and intestines.

indomethacin

Indomethacin works by blocking substances in the body that cause pain and inflammation. These substances are called prostaglandins. By blocking them, indomethacin helps to reduce swelling, pain, and stiffness.

Common Side Effects
glucagon
  • Nausea
  • Vomiting
  • Headache
  • Dizziness
  • Weakness
indomethacin
  • Headache
  • Dizziness
  • Upset stomach
  • Nausea
FAERS Reports
glucagon
  • Dyspnoea 354
  • Acute Kidney Injury 313
  • Hypotension 286
  • Hypoglycaemia 268
  • Condition Aggravated 244
indomethacin
  • Fatigue 1,102
  • Arthralgia 1,002
  • Headache 990
  • Pain 921
  • Nausea 907
Serious Warnings
glucagon

You should not take this medicine if you have a tumor in your adrenal gland called pheochromocytoma. It can cause a large increase in blood pressure. Also, you should not take it if you have a tumor called insulinoma, as it can cause low blood sugar. Do not take if you are allergic to glucagon.

indomethacin

Indomethacin may increase your risk of serious heart problems like heart attack or stroke, which can be fatal. This risk may occur early in treatment and may increase with longer use. You should not take this medicine before or after heart bypass surgery (CABG). Indomethacin can also increase your risk of serious stomach and intestine problems like bleeding, ulcers, and holes, which can be fatal. These problems can happen without warning. Elderly patients and those with a history of ulcers or GI bleeding are at higher risk.

Pregnancy
glucagon

Studies haven't shown any risk to the baby during pregnancy. Glucagon is not expected to cause harm to a breastfeeding infant because it will be broken down in the baby's stomach.

indomethacin

Using indomethacin during the later stages of pregnancy may harm your unborn baby. Limit use between 20 and 30 weeks of pregnancy, and avoid use after 30 weeks. Talk to your doctor if you are pregnant or plan to become pregnant.

Also Compare, Nearby Drugs

How to Read This glucagon vs indomethacin Comparison

glucagon is classified in the Glucagon (Hypoglycemia Rescue) drug class, while indomethacin sits within the Nonsteroidal Anti-Inflammatory Drug (NSAID) class. Drugs from different classes work through distinct mechanisms, so a head-to-head comparison illustrates trade-offs rather than equivalence. Both drugs are prescription-only, so a licensed provider must authorize use.

Adverse event totals above are pulled from the FDA's Adverse Event Reporting System (FAERS). For these top-ranked reactions alone, glucagon has 1,465 submissions while indomethacin has 4,922. Those figures reflect cumulative reporting volume, not per-patient risk, so older, widely dispensed drugs typically look worse on count alone. These two drugs have a known minor interaction flagged in FDA labeling, attributed to indomethacin can prevent glucagon from raising your blood sugar and may even cause your blood sugar to drop too low.. Serious warnings, pregnancy guidance, and contraindications can differ even when indications overlap.

A table cannot represent individual circumstances. Data here is sourced from FDA Structured Product Labels (SPL) and FAERS, both of which update as manufacturers and clinicians submit new information. This registry does not provide medical, treatment, substitution, or medication-change directions for glucagon or indomethacin.

Registry boundary: This comparison displays source-record fields and does not provide individualized medical direction.