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gentamicin vs tenofovir disoproxil

Side-by-side comparison of gentamicin and tenofovir disoproxil. Data from FDA drug databases (Orange Book, NDC Directory, recalls, shortages) covering 20,000+ approved drugs, plus CMS pricing; see our methodology.

minor Known Drug Interaction

Some examples include, but are not limited to, acyclovir, cidofovir, ganciclovir, valacyclovir, valganciclovir, aminoglycosides (e.g., gentamicin), and high-dose or multiple NSAIDs [see Warnings and Precautions ( 5.2)].

Recommendation: Your doctor should closely monitor your kidney function if you must take these two drugs at the same time.

Drug Class
gentamicin Aminoglycoside Antibiotic
tenofovir disoproxil Nucleotide Reverse Transcriptase Inhibitor
Type
gentamicin Prescription
tenofovir disoproxil Prescription
Summary
gentamicin

Gentamicin is an antibiotic medicine. It fights serious infections caused by certain bacteria.

tenofovir disoproxil

Tenofovir disoproxil fumarate is a medicine used to treat HIV and hepatitis B. It helps to lower the amount of virus in your body.

What It Treats
gentamicin

Gentamicin treats serious infections caused by certain bacteria. This includes infections in the blood, brain (meningitis), urinary tract, lungs, stomach area, skin, bone, and soft tissues. It can also treat bacterial infections in newborns.

tenofovir disoproxil

This medicine treats HIV-1 in adults and children at least 2 years old. It is always used with other HIV medicines. It also treats chronic hepatitis B in adults and children at least 12 years old.

How It Works
gentamicin

Gentamicin belongs to a class of drugs called aminoglycoside antibiotics. It works by stopping the growth of bacteria. This helps your body fight off the infection.

tenofovir disoproxil

Tenofovir disoproxil fumarate blocks an enzyme that HIV and hepatitis B need to multiply. This lowers the amount of virus in your body. It can help your immune system get stronger.

Common Side Effects
gentamicin

No common side effects listed.

tenofovir disoproxil
  • Rash
  • Diarrhea
  • Headache
  • Pain
  • Depression
FAERS Reports
gentamicin
  • Acute Kidney Injury 999
  • Pyrexia 751
  • Renal Failure 603
  • Diarrhoea 460
  • Sepsis 427
tenofovir disoproxil
  • Bone Density Decreased 10,625
  • Renal Injury 9,276
  • Skeletal Injury 8,327
  • Chronic Kidney Disease 7,247
  • Osteonecrosis 7,245
Serious Warnings
gentamicin

Gentamicin can potentially damage kidneys and cause nerve damage, including hearing loss. The risk is higher if you have kidney problems, receive high doses, or take it for a long time. Tell your doctor right away if you notice dizziness, ringing in your ears, changes in hearing, or kidney problems.

tenofovir disoproxil

After stopping this medicine, hepatitis B may get worse. Your doctor will monitor your liver closely for several months after you stop taking it. If needed, you may have to restart hepatitis B treatment.

Pregnancy
gentamicin

Tell your doctor if you are pregnant or breastfeeding. Gentamicin may harm your unborn baby. It is not known if gentamicin passes into breast milk.

tenofovir disoproxil

Tell your doctor if you are pregnant or plan to become pregnant. HIV-infected mothers should not breastfeed because of the risk of passing HIV to the baby.

Also Compare, Nearby Drugs

How to Read This gentamicin vs tenofovir disoproxil Comparison

gentamicin is classified in the Aminoglycoside Antibiotic drug class, while tenofovir disoproxil sits within the Nucleotide Reverse Transcriptase Inhibitor class. Drugs from different classes work through distinct mechanisms, so a head-to-head comparison illustrates trade-offs rather than equivalence. Both drugs are prescription-only, so a licensed provider must authorize use.

Adverse event totals above are pulled from the FDA's Adverse Event Reporting System (FAERS). For these top-ranked reactions alone, gentamicin has 3,240 submissions while tenofovir disoproxil has 42,720. Those figures reflect cumulative reporting volume, not per-patient risk, so older, widely dispensed drugs typically look worse on count alone. These two drugs have a known minor interaction flagged in FDA labeling, attributed to both of these medications can be hard on the kidneys, and taking them at the same time increases the risk of kidney damage.. Serious warnings, pregnancy guidance, and contraindications can differ even when indications overlap.

A table cannot substitute for clinical judgment. Effectiveness, tolerability, drug-drug interactions with your other medications, kidney and liver function, pregnancy status, insurance formulary, and price all feed into a decision that only a licensed prescriber can make responsibly. Data here is sourced from FDA Structured Product Labels (SPL) and FAERS, both of which update as manufacturers and clinicians submit new information. This page is for educational purposes only, is not medical advice, and should not be used to self-switch between gentamicin and tenofovir disoproxil - always consult your physician or pharmacist first.

Important: This comparison is for informational purposes only. Drug effects vary between individuals. Always consult your doctor or pharmacist for personalized medical advice.