gabapentin vs norethindrone
Side-by-side comparison of gabapentin and norethindrone. Data from FDA drug databases (Orange Book, NDC Directory, recalls, shortages) covering 20,000+ approved drugs, plus CMS pricing; see our methodology.
minor Known Drug Interaction
Oral Contraceptive Based on AUC and half-life, multiple-dose pharmacokinetic profiles of norethindrone and ethinyl estradiol following administration of tablets containing 2.5 mg of norethindrone acetate and 50 mcg of ethinyl estradiol were similar with and without coadministration of gabapentin (400 mg three times a day; N=13). The C max of norethindrone was 13% higher when it was coadministered with gabapentin; this interaction is not expected to be of clinical importance.
Recommendation: No changes are needed because this small increase is not expected to cause any problems.
Neurontin, Gralise
Camila, Errin
Gabapentin is a medicine that can treat nerve pain and seizures. It works by calming overactive nerves in the body.
Camila and Errin are progestin-only birth control pills. They help prevent pregnancy.
Gabapentin is used to manage nerve pain after shingles in adults. This is called postherpetic neuralgia. It is also used with other medicines to treat partial seizures in adults and children ages 3 and older who have epilepsy.
These pills are used to prevent pregnancy. They are a type of oral contraceptive, also known as birth control pills. When taken correctly, birth control pills are very effective at preventing pregnancy.
Gabapentin affects how nerves send signals to the brain. It is thought to work by decreasing the activity of overexcited nerve cells. This can reduce pain and prevent seizures.
Camila and Errin contain a progestin hormone. This hormone prevents pregnancy by stopping ovulation (the release of an egg from the ovary). It also thickens cervical mucus, making it harder for sperm to reach the egg.
- • Dizziness
- • Sleepiness
- • Swelling in arms and legs
- • Uncoordinated movements
- • Tiredness
- • Nausea
- • Vomiting
- • Gastrointestinal symptoms (like cramps and bloating)
- • Breakthrough bleeding or spotting
- • Changes in menstrual flow
- Tiredness 24,395
- Feeling sick to your stomach 21,942
- Aches and discomfort 20,748
- Loose or watery stools 17,456
- Pain in your head 17,287
- Feeling sick to your stomach 449
- Pain in your head 424
- Sudden feeling of warmth 370
- Feeling tired 322
- Aching or soreness 308
This medicine can cause a severe allergic reaction with fever, rash, and organ problems. Stop taking gabapentin and get medical help right away if you have trouble breathing or swelling of your face, lips, tongue, or throat. Do not drive or operate heavy machinery until you know how gabapentin affects you. Do not stop taking gabapentin suddenly, as this may increase seizures. Gabapentin may cause suicidal thoughts or actions. Watch for changes in mood or behavior. Using gabapentin with opioid medicines can cause very slow breathing, sedation, and death. Children ages 3 to 12 may have new or worsening behavior problems.
Cigarette smoking increases your risk of serious heart problems from birth control pills. This risk is higher if you are over 35 and smoke. You should not take this medication if you are over 35 and smoke.
Gabapentin may cause harm to an unborn baby based on animal studies. If you are pregnant or plan to become pregnant, talk to your doctor. Gabapentin passes into breast milk. The effects on a nursing baby are not known.
These pills should not be taken if you are pregnant or think you might be pregnant. Talk to your doctor about other birth control options if you are breastfeeding.
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How to Read This gabapentin vs norethindrone Comparison
gabapentin is classified in the Anticonvulsant / Nerve Pain Agent drug class, while norethindrone sits within the Progestin-Only Oral Contraceptive class. Drugs from different classes work through distinct mechanisms, so a head-to-head comparison illustrates trade-offs rather than equivalence. Both drugs are prescription-only, so a licensed provider must authorize use.
Adverse event totals above are pulled from the FDA's Adverse Event Reporting System (FAERS). For these top-ranked reactions alone, gabapentin has 101,828 submissions while norethindrone has 1,873. Those figures reflect cumulative reporting volume, not per-patient risk, so older, widely dispensed drugs typically look worse on count alone. These two drugs have a known minor interaction flagged in FDA labeling, attributed to gabapentin slightly raises the peak level of the birth control hormone in your blood, but the change is very small.. Serious warnings, pregnancy guidance, and contraindications can differ even when indications overlap.
A table cannot substitute for clinical judgment. Effectiveness, tolerability, drug-drug interactions with your other medications, kidney and liver function, pregnancy status, insurance formulary, and price all feed into a decision that only a licensed prescriber can make responsibly. Data here is sourced from FDA Structured Product Labels (SPL) and FAERS, both of which update as manufacturers and clinicians submit new information. This page is for educational purposes only, is not medical advice, and should not be used to self-switch between gabapentin and norethindrone - always consult your physician or pharmacist first.
Important: This comparison is for informational purposes only. Drug effects vary between individuals. Always consult your doctor or pharmacist for personalized medical advice.