folic acid vs infliximab

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Side-by-side comparison of folic acid and infliximab. Data from FDA drug databases (Orange Book, NDC Directory, recalls, shortages) covering 20,000+ approved drugs, plus CMS pricing; see our methodology.

minor Known Drug Interaction

In RA, concomitant medications besides MTX were nonsteroidal anti-inflammatory agents (NSAIDs), folic acid, corticosteroids and/or narcotics. In PsA clinical trials, concomitant medications included MTX in approximately half of the patients as well as NSAIDs, folic acid and corticosteroids.

Drug Class
folic acid B Vitamin (Folate) Supplement
infliximab TNF-Alpha Inhibitor (Biologic)
Type
folic acid Over-the-Counter
infliximab Prescription
Summary
folic acid

Integra FTM is a medicine that helps treat iron and folate deficiencies. It is also used during pregnancy to prevent and treat iron deficiency and provide folic acid.

infliximab

Inflectra is a medicine that blocks a protein called TNF. It is used to treat autoimmune diseases and reduce inflammation.

What It Treats
folic acid

Integra FTM treats iron deficiency anemia and folate deficiency anemia. It is also used during pregnancy to prevent and treat iron deficiency. This medicine also provides a maintenance dosage of folic acid during pregnancy.

infliximab

Inflectra treats Crohn's disease in adults and children (6+). It helps reduce symptoms and keep the disease under control. It also treats ulcerative colitis, rheumatoid arthritis, ankylosing spondylitis, psoriatic arthritis, and plaque psoriasis.

How It Works
folic acid

Integra FTM contains two types of iron that your body can use. These iron types help to increase the amount of iron in your blood. Folic acid is a B vitamin that helps your body make new blood cells.

infliximab

Inflectra blocks a protein in your body called tumor necrosis factor (TNF). TNF can cause inflammation and damage in autoimmune diseases. By blocking TNF, Inflectra can reduce inflammation and improve symptoms.

Common Side Effects
folic acid
  • Upset stomach
  • Nausea
  • Diarrhea
  • Constipation
  • Heartburn
infliximab
  • Infections (like colds, sinus infections, and sore throat)
  • Infusion-related reactions
  • Headache
  • Abdominal pain
FAERS Reports
folic acid
  • Fatigue 23,332
  • Pain 23,054
  • Arthralgia 19,495
  • Rheumatoid Arthritis 17,528
  • Nausea 15,633
infliximab
  • Infusion Related Reaction 18,648
  • Condition Aggravated 18,301
  • Rheumatoid Arthritis 18,136
  • Pain 18,107
  • Arthralgia 16,853
Serious Warnings
folic acid

Accidental overdose of iron-containing products is a leading cause of fatal poisoning in young children. Keep this medicine away from children. If someone overdoses, call a doctor or poison control center right away. Folic acid alone is not the right treatment for pernicious anemia or other megaloblastic anemias where Vitamin B12 is lacking.

infliximab

Inflectra can increase your risk of serious infections that may lead to hospitalization or death. Tell your doctor if you have any infection symptoms. You should be tested for tuberculosis (TB) before starting Inflectra. Some people, especially children and young adults, have developed cancers like lymphoma while taking TNF blockers. Some of these cancers have been fatal.

Pregnancy
folic acid

Integra FTM can be used during pregnancy to prevent and treat iron deficiency and to provide folic acid. Talk to your doctor before taking this medicine if you are pregnant or breastfeeding.

infliximab

Tell your doctor if you are pregnant or plan to become pregnant. Inflectra can pass to your baby during pregnancy, mainly in the third trimester. Live vaccines are not recommended for at least 6 months after birth for babies exposed to Inflectra in the womb.

Also Compare, Nearby Drugs

How to Read This folic acid vs infliximab Comparison

folic acid is classified in the B Vitamin (Folate) Supplement drug class, while infliximab sits within the TNF-Alpha Inhibitor (Biologic) class. Drugs from different classes work through distinct mechanisms, so a head-to-head comparison illustrates trade-offs rather than equivalence. Both drugs are split between OTC and prescription status, which affects access and supervision.

Adverse event totals above are pulled from the FDA's Adverse Event Reporting System (FAERS). For these top-ranked reactions alone, folic acid has 99,042 submissions while infliximab has 90,045. Those figures reflect cumulative reporting volume, not per-patient risk, so older, widely dispensed drugs typically look worse on count alone. These two drugs have a known minor interaction flagged in FDA labeling, attributed to there is no known negative interaction between these two drugs, and they are frequently used together to manage rheumatoid arthritis.. Serious warnings, pregnancy guidance, and contraindications can differ even when indications overlap.

A table cannot represent individual circumstances. Data here is sourced from FDA Structured Product Labels (SPL) and FAERS, both of which update as manufacturers and clinicians submit new information. This registry does not provide medical, treatment, substitution, or medication-change directions for folic acid or infliximab.

Registry boundary: This comparison displays source-record fields and does not provide individualized medical direction.