fluoxetine vs moxifloxacin

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Side-by-side comparison of fluoxetine and moxifloxacin. Data from FDA drug databases (Orange Book, NDC Directory, recalls, shortages) covering 20,000+ approved drugs, plus CMS pricing; see our methodology.

minor Known Drug Interaction

These include: specific antipsychotics (e.g., ziprasidone, iloperidone, chlorpromazine, mesoridazine, droperidol); specific antibiotics (e.g., erythromycin, gatifloxacin, moxifloxacin, sparfloxacin); Class 1A antiarrhythmic medications (e.g., quinidine, procainamide); Class III antiarrhythmics (e.g., amiodarone, sotalol); and others (e.g., pentamidine, levomethadyl acetate, methadone, halofantrine, mefloquine, dolasetron mesylate, probucol or tacrolimus).

Drug Class
fluoxetine Selective Serotonin Reuptake Inhibitor (SSRI)
moxifloxacin Fluoroquinolone Antibiotic
Type
fluoxetine Prescription
moxifloxacin Prescription
Summary
fluoxetine

Fluoxetine is a medicine that can help treat depression and other mental health conditions. It belongs to a class of drugs called selective serotonin reuptake inhibitors (SSRIs).

moxifloxacin

Moxifloxacin is an antibiotic that fights bacteria in your body. It is used to treat different types of infections.

What It Treats
fluoxetine

Fluoxetine can treat major depressive disorder in adults and children. It also treats obsessive-compulsive disorder (OCD) in adults and children. Fluoxetine can help with bulimia nervosa (an eating disorder) and panic disorder. Sometimes, it is used with another medicine called olanzapine to treat depression related to bipolar disorder.

moxifloxacin

Moxifloxacin treats infections like pneumonia, skin infections, and infections in your stomach area. It can also treat sinus infections, bronchitis, and plague. This medicine should only be used to treat infections that are proven or very likely to be caused by bacteria that it can kill.

How It Works
fluoxetine

Fluoxetine works by increasing the amount of serotonin in your brain. Serotonin is a chemical that helps regulate mood. By increasing serotonin, fluoxetine can help improve mood and reduce symptoms of depression, OCD, and other conditions.

moxifloxacin

Moxifloxacin belongs to a class of drugs called fluoroquinolones. It works by stopping bacteria from multiplying. This helps your body fight off the infection.

Common Side Effects
fluoxetine
  • Abnormal dreams
  • Problems ejaculating
  • Loss of appetite
  • Feeling anxious
  • Feeling weak
moxifloxacin
  • Nausea
  • Diarrhea
  • Headache
  • Dizziness
FAERS Reports
fluoxetine
  • Drug Interaction 3,335
  • Toxicity To Various Agents 3,316
  • Nausea 3,233
  • Fatigue 3,156
  • Completed Suicide 2,904
moxifloxacin
  • Dyspnoea 1,225
  • Pneumonia 1,142
  • Vomiting 1,101
  • Drug Hypersensitivity 1,073
  • Asthma 910
Serious Warnings
fluoxetine

Antidepressants may increase the risk of suicidal thoughts and behaviors in children, teenagers, and young adults. Watch closely for worsening depression or suicidal thoughts. Tell your doctor right away if you notice any changes in mood or behavior. Fluoxetine is not approved for use in children younger than 7 years old.

moxifloxacin

Moxifloxacin can cause serious side effects, even if they don't happen to everyone. These include tendon problems, nerve damage, and central nervous system problems. If you have myasthenia gravis, moxifloxacin can make your muscle weakness worse. If you experience any of these serious side effects, stop taking moxifloxacin immediately and talk to your doctor. Because of these risks, moxifloxacin should only be used when other treatment options are not available for sinus infections or bronchitis.

Pregnancy
fluoxetine

Talk to your doctor if you are pregnant or plan to become pregnant. Fluoxetine should only be used during pregnancy if the benefit outweighs the risk to the baby. Breastfeeding is not recommended while taking fluoxetine.

moxifloxacin

Talk to your doctor if you are pregnant or plan to become pregnant. Moxifloxacin may harm your unborn baby. It is not known if moxifloxacin passes into breast milk, so talk to your doctor if you are breastfeeding.

Also Compare, Nearby Drugs

How to Read This fluoxetine vs moxifloxacin Comparison

fluoxetine is classified in the Selective Serotonin Reuptake Inhibitor (SSRI) drug class, while moxifloxacin sits within the Fluoroquinolone Antibiotic class. Drugs from different classes work through distinct mechanisms, so a head-to-head comparison illustrates trade-offs rather than equivalence. Both drugs are prescription-only, so a licensed provider must authorize use.

Adverse event totals above are pulled from the FDA's Adverse Event Reporting System (FAERS). For these top-ranked reactions alone, fluoxetine has 15,944 submissions while moxifloxacin has 5,451. Those figures reflect cumulative reporting volume, not per-patient risk, so older, widely dispensed drugs typically look worse on count alone. These two drugs have a known minor interaction flagged in FDA labeling, attributed to both of these drugs can change the way your heart beats. using them together may increase the risk of developing a dangerous heart rhythm.. Serious warnings, pregnancy guidance, and contraindications can differ even when indications overlap.

A table cannot represent individual circumstances. Data here is sourced from FDA Structured Product Labels (SPL) and FAERS, both of which update as manufacturers and clinicians submit new information. This registry does not provide medical, treatment, substitution, or medication-change directions for fluoxetine or moxifloxacin.

Registry boundary: This comparison displays source-record fields and does not provide individualized medical direction.