fluoxetine vs insulin human/insulin isophane
Side-by-side comparison of fluoxetine and insulin human/insulin isophane. Data from FDA drug databases (Orange Book, NDC Directory, recalls, shortages) covering 20,000+ approved drugs, plus CMS pricing; see our methodology.
moderate Known Drug Interaction
7 DRUG INTERACTIONS Table 1: Clinically Significant Drug Interactions with HUMULIN 70/30 Drugs that May Increase the Risk of Hypoglycemia Drugs: Antidiabetic agents, ACE inhibitors, angiotensin II receptor blocking agents, disopyramide, fibrates, fluoxetine, monoamine oxidase inhibitors, pentoxifylline, pramlintide, salicylates, somatostatin analog (e.g., octreotide), and sulfonamide antibiotics Intervention: Dose adjustment and increased frequency of glucose monitoring may be required when HUMULIN 70/30 is co-administered with these drugs.
Recommendation: Your doctor may need to adjust your dose and you should check your blood sugar levels more frequently.
Prozac, Sarafem
Humulin 70/30
Fluoxetine is a medicine that can help treat depression and other mental health conditions. It belongs to a class of drugs called selective serotonin reuptake inhibitors (SSRIs).
Humulin 70/30 is a mix of two types of insulin. It helps control blood sugar in adults with diabetes.
Fluoxetine can treat major depressive disorder in adults and children. It also treats obsessive-compulsive disorder (OCD) in adults and children. Fluoxetine can help with bulimia nervosa (an eating disorder) and panic disorder. Sometimes, it is used with another medicine called olanzapine to treat depression related to bipolar disorder.
Humulin 70/30 is used to improve blood sugar control in adults with diabetes. Diabetes is a condition where your body does not make enough insulin or cannot use insulin properly. This medicine helps your body use sugar from the food you eat for energy.
Fluoxetine works by increasing the amount of serotonin in your brain. Serotonin is a chemical that helps regulate mood. By increasing serotonin, fluoxetine can help improve mood and reduce symptoms of depression, OCD, and other conditions.
This medicine is a mix of two insulins: one that works quickly and one that works longer. The short-acting insulin helps control blood sugar after meals. The intermediate-acting insulin works between meals and during the night.
- • Abnormal dreams
- • Problems ejaculating
- • Loss of appetite
- • Feeling anxious
- • Feeling weak
- • Low blood sugar (hypoglycemia)
- • Allergic reactions like redness and swelling at the injection site
- • Skin changes at the injection site
- • Weight gain
- The medicine is interacting with another medicine 3,336
- Harmful effect from different substances 3,316
- Feeling sick to your stomach 3,233
- Feeling tired 3,155
- Death by suicide 2,904
- High blood sugar 10,557
- Low blood sugar 3,451
- Wrong dose given 2,164
- Low blood sugar 1,532
- Feeling sick to your stomach 1,473
Antidepressants may increase the risk of suicidal thoughts and behaviors in children, teenagers, and young adults. Watch closely for worsening depression or suicidal thoughts. Tell your doctor right away if you notice any changes in mood or behavior. Fluoxetine is not approved for use in children younger than 7 years old.
Never share a Humulin 70/30 KwikPen or syringe with anyone else, even if the needle is changed. Sharing pens or syringes can spread blood-borne diseases. Changes in your insulin dose should be done carefully with your doctor's supervision. Low blood sugar can be life-threatening. Fluid retention and heart failure can occur if you also take thiazolidinediones (TZDs).
Talk to your doctor if you are pregnant or plan to become pregnant. Fluoxetine should only be used during pregnancy if the benefit outweighs the risk to the baby. Breastfeeding is not recommended while taking fluoxetine.
Tell your doctor if you are pregnant or plan to become pregnant. Good control of diabetes is important during pregnancy. This medicine may pass into breast milk, but it is not expected to harm your baby.
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How to Read This fluoxetine vs insulin human/insulin isophane Comparison
fluoxetine is classified in the Selective Serotonin Reuptake Inhibitor (SSRI) drug class, while insulin human/insulin isophane sits within the Intermediate-Acting Insulin Combination class. Drugs from different classes work through distinct mechanisms, so a head-to-head comparison illustrates trade-offs rather than equivalence. Both drugs are prescription-only, so a licensed provider must authorize use.
Adverse event totals above are pulled from the FDA's Adverse Event Reporting System (FAERS). For these top-ranked reactions alone, fluoxetine has 15,944 submissions while insulin human/insulin isophane has 19,177. Those figures reflect cumulative reporting volume, not per-patient risk, so older, widely dispensed drugs typically look worse on count alone. These two drugs have a known moderate interaction flagged in FDA labeling, attributed to fluoxetine can increase the risk of low blood sugar when taken with insulin.. Serious warnings, pregnancy guidance, and contraindications can differ even when indications overlap.
A table cannot substitute for clinical judgment. Effectiveness, tolerability, drug-drug interactions with your other medications, kidney and liver function, pregnancy status, insurance formulary, and price all feed into a decision that only a licensed prescriber can make responsibly. Data here is sourced from FDA Structured Product Labels (SPL) and FAERS, both of which update as manufacturers and clinicians submit new information. This page is for educational purposes only, is not medical advice, and should not be used to self-switch between fluoxetine and insulin human/insulin isophane - always consult your physician or pharmacist first.
Important: This comparison is for informational purposes only. Drug effects vary between individuals. Always consult your doctor or pharmacist for personalized medical advice.