estradiol vs ethinyl estradiol/norgestimate
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Side-by-side comparison of estradiol and ethinyl estradiol/norgestimate. Data from FDA drug databases (Orange Book, NDC Directory, recalls, shortages) covering 20,000+ approved drugs, plus CMS pricing; see our methodology.
minor Known Drug Interaction
No drug-drug interaction studies were conducted with levonorgestrel and ethinyl estradiol tablets. ( 7.1 ) 7.1 Effects of Other Drugs on Combined Oral Contraceptives Substances decreasing the plasma concentrations of COCs and potentially diminishing the efficacy of COCs: Table 5 includes substances that demonstrated an important drug interaction with levonorgestrel and ethinyl estradiol tablets. Colesevelam Clinical effect Concomitant use of COCs with colesevelam significantly decreases systemic exposure of ethinyl estradiol [see Clinical Pharmacology (12.3) ] .
Estrace, Vivelle-Dot
Ortho Tri-Cyclen, Sprintec
Iclevia is a birth control pill. It contains two hormones, a progestin and an estrogen, that work together to prevent pregnancy.
Iclevia is a birth control pill. It contains two hormones, levonorgestrel and ethinyl estradiol, to prevent pregnancy.
Iclevia is used by women who can get pregnant to prevent pregnancy. It contains two types of hormones. These hormones stop you from releasing an egg and also change the lining of your uterus, which prevents pregnancy.
Iclevia is used by women who can get pregnant to prevent pregnancy. It contains two hormones, a progestin and an estrogen. These hormones work together to prevent ovulation and change the lining of the uterus.
Iclevia contains two hormones: levonorgestrel (a progestin) and ethinyl estradiol (an estrogen). These hormones prevent pregnancy by stopping ovulation (the release of an egg from the ovary). They also change the lining of the uterus to prevent a fertilized egg from implanting.
Iclevia contains two hormones: levonorgestrel and ethinyl estradiol. These hormones prevent ovulation (the release of an egg from the ovary). They also change the lining of the uterus, making it harder for a fertilized egg to implant.
- • Headache
- • Heavy menstrual bleeding
- • Nausea
- • Painful periods
- • Acne
- • Headache
- • Heavier menstrual bleeding
- • Nausea
- • Painful periods
- • Acne
- Product Adhesion Issue 5,172
- Headache 5,036
- Nausea 4,754
- Fatigue 4,511
- Pain 3,480
No adverse event reports.
Cigarette smoking increases your risk of serious heart problems from birth control pills. This risk is higher if you are over 35 and smoke more cigarettes. You should not take Iclevia if you are over 35 and smoke.
Cigarette smoking increases your risk of serious heart problems from birth control pills. This risk is higher if you are over 35 and smoke more cigarettes. If you are over 35 and smoke, you should not take Iclevia.
Do not use Iclevia if you are pregnant. If you become pregnant while taking Iclevia, stop taking it right away. Iclevia can reduce milk production, so you may want to use a different birth control method while breastfeeding.
Do not use Iclevia if you are pregnant. Iclevia can reduce milk production while breastfeeding, so another form of birth control is recommended. Talk to your doctor about the best option for you.
Also Compare, Nearby Drugs
How to Read This estradiol vs ethinyl estradiol/norgestimate Comparison
estradiol is classified in the Estrogen Hormone drug class, while ethinyl estradiol/norgestimate sits within the Combined Oral Contraceptive class. Drugs from different classes work through distinct mechanisms, so a head-to-head comparison illustrates trade-offs rather than equivalence. Both drugs are prescription-only, so a licensed provider must authorize use.
Adverse event totals above are pulled from the FDA's Adverse Event Reporting System (FAERS). For these top-ranked reactions alone, estradiol has 22,953 submissions while ethinyl estradiol/norgestimate has 0. Those figures reflect cumulative reporting volume, not per-patient risk, so older, widely dispensed drugs typically look worse on count alone. These two drugs have a known minor interaction flagged in FDA labeling, attributed to colesevelam can trap the birth control hormones in your gut and stop them from being absorbed into your body. this can make your birth control less effective at preventing pregnancy.. Serious warnings, pregnancy guidance, and contraindications can differ even when indications overlap.
A table cannot represent individual circumstances. Data here is sourced from FDA Structured Product Labels (SPL) and FAERS, both of which update as manufacturers and clinicians submit new information. This registry does not provide medical, treatment, substitution, or medication-change directions for estradiol or ethinyl estradiol/norgestimate.
Registry boundary: This comparison displays source-record fields and does not provide individualized medical direction.