erythromycin vs felbamate
Side-by-side comparison of erythromycin and felbamate. Data from FDA drug databases (Orange Book, NDC Directory, recalls, shortages) covering 20,000+ approved drugs, plus CMS pricing; see our methodology.
minor Known Drug Interaction
Effects of Erythromycin on Felbamate The coadministration of erythromycin (1000 mg/day) for 10 days did not alter the pharmacokinetic parameters of C max , C min , AUC, Cl/kg or T max at felbamate daily doses of 3000 or 3600 mg/day in 10 otherwise healthy subjects with epilepsy.
Recommendation: You can take these two drugs together without needing to change your felbamate dose.
E-Mycin, Ery-Tab
Felbatol
Erythromycin Topical Solution is a medicine that you put on your skin to treat acne. It contains an antibiotic to help clear up your skin.
Felbamate is a medicine used to treat seizures. It is usually only prescribed when other treatments haven't worked well enough due to the risk of serious side effects.
Erythromycin Topical Solution treats acne vulgaris. This medicine helps to reduce acne on your face, neck, shoulders, chest, and back. It works by fighting the bacteria that cause acne.
Felbamate treats partial seizures in adults, both with and without generalization. It is also used as an add-on treatment for seizures related to Lennox-Gastaut syndrome in children. Because of the risk of very serious side effects, you should only use this medicine if other treatments have not worked well enough.
Erythromycin is a macrolide antibiotic. It works by stopping the growth of bacteria. This helps to reduce inflammation and clear up acne.
Felbamate is an anticonvulsant, meaning it helps to control seizures. The exact way it works in the brain is not fully understood. It is thought to affect certain chemicals in the brain that are involved in seizures.
- • Peeling
- • Dryness
- • Itching
- • Redness
- • Oily skin
- • Loss of appetite
- • Vomiting
- • Trouble sleeping
- • Feeling sick to your stomach
- • Headache
- Drug Hypersensitivity 4,088
- Nausea 1,271
- Vomiting 1,121
- Diarrhoea 1,069
- Dyspnoea 1,023
- Seizure 345
- Convulsion 124
- Sleepiness 108
- Condition getting worse 92
- Tiredness 85
You should not use this medicine if you are allergic to any of its ingredients.
Felbamate can cause a severe type of anemia called aplastic anemia. This condition is very serious and can be deadly. Because of this risk, felbamate should only be used if your epilepsy is very severe and other treatments have not worked. Felbamate can also cause liver failure. Talk to your doctor about these risks before starting felbamate.
It is not known if erythromycin topical solution can harm an unborn baby. Talk to your doctor if you are pregnant or breastfeeding.
It is not known if felbamate can harm an unborn baby. Talk to your doctor if you are pregnant or plan to become pregnant. It is also not known if felbamate passes into breast milk, so talk to your doctor if you are breastfeeding.
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How to Read This erythromycin vs felbamate Comparison
erythromycin is classified in the Macrolide Antibiotic drug class, while felbamate sits within the Anticonvulsant class. Drugs from different classes work through distinct mechanisms, so a head-to-head comparison illustrates trade-offs rather than equivalence. Both drugs are prescription-only, so a licensed provider must authorize use.
Adverse event totals above are pulled from the FDA's Adverse Event Reporting System (FAERS). For these top-ranked reactions alone, erythromycin has 8,572 submissions while felbamate has 754. Those figures reflect cumulative reporting volume, not per-patient risk, so older, widely dispensed drugs typically look worse on count alone. These two drugs have a known minor interaction flagged in FDA labeling, attributed to erythromycin does not change the amount of felbamate that stays in your system.. Serious warnings, pregnancy guidance, and contraindications can differ even when indications overlap.
A table cannot substitute for clinical judgment. Effectiveness, tolerability, drug-drug interactions with your other medications, kidney and liver function, pregnancy status, insurance formulary, and price all feed into a decision that only a licensed prescriber can make responsibly. Data here is sourced from FDA Structured Product Labels (SPL) and FAERS, both of which update as manufacturers and clinicians submit new information. This page is for educational purposes only, is not medical advice, and should not be used to self-switch between erythromycin and felbamate - always consult your physician or pharmacist first.
Important: This comparison is for informational purposes only. Drug effects vary between individuals. Always consult your doctor or pharmacist for personalized medical advice.