erythromycin vs ezetimibe/simvastatin
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Side-by-side comparison of erythromycin and ezetimibe/simvastatin. Data from FDA drug databases (Orange Book, NDC Directory, recalls, shortages) covering 20,000+ approved drugs, plus CMS pricing; see our methodology.
minor Known Drug Interaction
Examples: Select azole anti-fungals (e.g., itraconazole, ketoconazole, posaconazole, and voriconazole), select macrolide antibiotics (e.g., erythromycin and clarithromycin, telithromycin), select HIV protease inhibitors (e.g., nelfinavir, ritonavir, and darunavir/ritonavir), select HCV protease inhibitors (e.g., boceprevir and telaprevir), cobicistat-containing products, and nefazodone.
E-Mycin, Ery-Tab
Vytorin
Erythromycin Topical Solution is a medicine that you put on your skin to treat acne. It contains an antibiotic to help clear up your skin.
Vytorin is a combination medicine that contains ezetimibe and simvastatin. It helps lower bad cholesterol (LDL-C) in your blood.
Erythromycin Topical Solution treats acne vulgaris. This medicine helps to reduce acne on your face, neck, shoulders, chest, and back. It works by fighting the bacteria that cause acne.
Vytorin is used along with a healthy diet to lower high LDL cholesterol. It is used in adults with primary hyperlipidemia and in adults and children 10 years and older with heterozygous familial hypercholesterolemia (HeFH). Vytorin can also be used with other cholesterol-lowering treatments for adults with homozygous familial hypercholesterolemia (HoFH). Simvastatin, one of the drugs in Vytorin, can also lower the risk of heart problems like heart attack and stroke in adults with heart disease, blood vessel disease, or diabetes.
Erythromycin is a macrolide antibiotic. It works by stopping the growth of bacteria. This helps to reduce inflammation and clear up acne.
Ezetimibe reduces the amount of cholesterol your body absorbs from food. Simvastatin belongs to a class of drugs called statins. Statins lower cholesterol by blocking a substance your body needs to make cholesterol.
- • Peeling
- • Dryness
- • Itching
- • Redness
- • Oily skin
- • Headache
- • Increased liver enzyme (ALT)
- • Muscle pain
- • Upper respiratory tract infection
- • Diarrhea
- Drug Hypersensitivity 4,088
- Nausea 1,271
- Vomiting 1,121
- Diarrhoea 1,069
- Dyspnoea 1,023
- Feeling sick to your stomach 1,008
- Feeling tired 771
- Feeling lightheaded 731
- General pain 702
- Muscle pain 669
You should not use this medicine if you are allergic to any of its ingredients.
Vytorin can cause muscle problems, including myopathy and rhabdomyolysis. Tell your doctor right away if you have unexplained muscle pain, tenderness, or weakness, especially if you also have a fever or feel sick. Vytorin can also cause liver problems. Your doctor may do blood tests to check your liver before you start taking Vytorin and while you take it.
It is not known if erythromycin topical solution can harm an unborn baby. Talk to your doctor if you are pregnant or breastfeeding.
Do not take Vytorin if you are pregnant. It can harm your unborn baby. Talk to your doctor if you are breastfeeding or plan to breastfeed, as it is not recommended during treatment with Vytorin.
Also Compare, Nearby Drugs
Compare erythromycin with
How to Read This erythromycin vs ezetimibe/simvastatin Comparison
erythromycin is classified in the Macrolide Antibiotic drug class, while ezetimibe/simvastatin sits within the Cholesterol Absorption Inhibitor / Statin Combination class. Drugs from different classes work through distinct mechanisms, so a head-to-head comparison illustrates trade-offs rather than equivalence. Both drugs are prescription-only, so a licensed provider must authorize use.
Adverse event totals above are pulled from the FDA's Adverse Event Reporting System (FAERS). For these top-ranked reactions alone, erythromycin has 8,572 submissions while ezetimibe/simvastatin has 3,881. Those figures reflect cumulative reporting volume, not per-patient risk, so older, widely dispensed drugs typically look worse on count alone. These two drugs have a known minor interaction flagged in FDA labeling, attributed to this antibiotic interferes with how your body gets rid of simvastatin. this leads to higher amounts of the drug in your blood, which increases the risk of muscle pain and weakness.. Serious warnings, pregnancy guidance, and contraindications can differ even when indications overlap.
A table cannot represent individual circumstances. Data here is sourced from FDA Structured Product Labels (SPL) and FAERS, both of which update as manufacturers and clinicians submit new information. This registry does not provide medical, treatment, substitution, or medication-change directions for erythromycin or ezetimibe/simvastatin.
Registry boundary: This comparison displays source-record fields and does not provide individualized medical direction.