drospirenone/ethinyl estradiol vs griseofulvin

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Side-by-side comparison of drospirenone/ethinyl estradiol and griseofulvin. Data from FDA drug databases (Orange Book, NDC Directory, recalls, shortages) covering 20,000+ approved drugs, plus CMS pricing; see our methodology.

minor Known Drug Interaction

Some drugs or herbal products that may decrease the effectiveness of hormonal contraceptives include phenytoin, barbiturates, carbamazepine, bosentan, felbamate, griseofulvin, oxcarbazepine, rifampin, topiramate and products containing St.

Drug Class
drospirenone/ethinyl estradiol Combined Oral Contraceptive
griseofulvin Antifungal
Type
drospirenone/ethinyl estradiol Prescription
griseofulvin Prescription
Summary
drospirenone/ethinyl estradiol

This medicine contains drospirenone and ethinyl estradiol, which are hormones that prevent pregnancy. It also contains folate to help raise folate levels.

griseofulvin

Griseofulvin is an antifungal medicine. It treats fungal infections of the skin, hair, and nails.

What It Treats
drospirenone/ethinyl estradiol

This medicine can prevent pregnancy. It can also treat symptoms of premenstrual dysphoric disorder (PMDD) if you also want birth control. This medicine can also treat moderate acne in women at least 14 years old who also want birth control.

griseofulvin

This medicine treats fungal infections called dermatophyte infections. These infections can affect your skin (tinea corporis, tinea cruris, tinea barbae), feet (tinea pedis), scalp (tinea capitis), or nails (tinea unguium). Make sure a lab test confirms you have a fungal infection before you start taking this medicine. This medicine will not work for bacterial or yeast infections.

How It Works
drospirenone/ethinyl estradiol

This medicine prevents pregnancy by stopping ovulation (the release of an egg from the ovary). It also changes the lining of the uterus, making it harder for a fertilized egg to implant. The folate helps increase folate levels in the body.

griseofulvin

Griseofulvin stops fungi from growing and multiplying. It binds to a protein in the fungi. This disrupts the fungi's cell structure and prevents it from spreading.

Common Side Effects
drospirenone/ethinyl estradiol
  • Headache or migraine
  • Irregular periods
  • Nausea or vomiting
  • Breast pain or tenderness
griseofulvin
  • Headache
  • Nausea
  • Vomiting
  • Diarrhea
  • Fatigue
FAERS Reports
drospirenone/ethinyl estradiol
  • Pain 13,037
  • Injury 10,860
  • Blood clot in the lungs 9,316
  • Blood clot in a deep vein 8,390
  • Anxiety 6,996
griseofulvin
  • Headache 15
  • Pyrexia 11
  • Rash 11
  • Diarrhoea 10
  • Drug Hypersensitivity 10
Serious Warnings
drospirenone/ethinyl estradiol

Cigarette smoking increases your risk of serious heart problems when using birth control pills. This risk is higher if you are over 35 and smoke. Women over 35 who smoke should not use this medicine.

griseofulvin

Griseofulvin can cause liver problems. If you have liver failure or a history of sensitivity to griseofulvin, you should not take this medicine. Do not take this medicine if you have porphyria. Griseofulvin can harm an unborn baby, so do not take it if you are pregnant or could become pregnant.

Pregnancy
drospirenone/ethinyl estradiol

Do not use this medicine if you are pregnant. This medicine can reduce milk production while breastfeeding. If possible, use other birth control methods until you stop breastfeeding.

griseofulvin

Do not take this medicine if you are pregnant. It can cause harm to your unborn baby. Talk to your doctor about birth control options if you are a woman who could become pregnant.

Also Compare, Nearby Drugs

How to Read This drospirenone/ethinyl estradiol vs griseofulvin Comparison

drospirenone/ethinyl estradiol is classified in the Combined Oral Contraceptive drug class, while griseofulvin sits within the Antifungal class. Drugs from different classes work through distinct mechanisms, so a head-to-head comparison illustrates trade-offs rather than equivalence. Both drugs are prescription-only, so a licensed provider must authorize use.

Adverse event totals above are pulled from the FDA's Adverse Event Reporting System (FAERS). For these top-ranked reactions alone, drospirenone/ethinyl estradiol has 48,599 submissions while griseofulvin has 57. Those figures reflect cumulative reporting volume, not per-patient risk, so older, widely dispensed drugs typically look worse on count alone. These two drugs have a known minor interaction flagged in FDA labeling, attributed to griseofulvin causes your body to get rid of birth control hormones more quickly than it should. this can make your birth control fail to prevent pregnancy.. Serious warnings, pregnancy guidance, and contraindications can differ even when indications overlap.

A table cannot represent individual circumstances. Data here is sourced from FDA Structured Product Labels (SPL) and FAERS, both of which update as manufacturers and clinicians submit new information. This registry does not provide medical, treatment, substitution, or medication-change directions for drospirenone/ethinyl estradiol or griseofulvin.

Registry boundary: This comparison displays source-record fields and does not provide individualized medical direction.