dronabinol vs erythromycin

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Side-by-side comparison of dronabinol and erythromycin. Data from FDA drug databases (Orange Book, NDC Directory, recalls, shortages) covering 20,000+ approved drugs, plus CMS pricing; see our methodology.

minor Known Drug Interaction

Monitor for potentially increased dronabinol-related adverse reactions when dronabinol capsules are co-administered with inhibitors of CYP2C9 (e.g., amiodarone, fluconazole) and inhibitors of CYP3A4 enzymes (e.g., ketoconazole, itraconazole, clarithromycin, ritonavir, erythromycin, grapefruit juice).

Drug Class
dronabinol Cannabinoid Antiemetic
erythromycin Macrolide Antibiotic
Type
dronabinol Prescription
erythromycin Prescription
Summary
dronabinol

Dronabinol capsules contain a synthetic form of THC, the active ingredient in marijuana. It is used to treat loss of appetite in AIDS patients and nausea/vomiting from chemotherapy.

erythromycin

Erythromycin Topical Solution is a medicine that you put on your skin to treat acne. It contains an antibiotic to help clear up your skin.

What It Treats
dronabinol

Dronabinol is used to treat loss of appetite and weight loss in adults with Acquired Immune Deficiency Syndrome (AIDS). It also helps with nausea and vomiting caused by cancer chemotherapy when other treatments don't work well. Dronabinol can help you eat more and feel less sick.

erythromycin

Erythromycin Topical Solution treats acne vulgaris. This medicine helps to reduce acne on your face, neck, shoulders, chest, and back. It works by fighting the bacteria that cause acne.

How It Works
dronabinol

Dronabinol works by activating cannabinoid receptors in your brain. These receptors affect appetite, mood, and the sensation of nausea. By activating these receptors, dronabinol can increase appetite and reduce nausea and vomiting.

erythromycin

Erythromycin is a macrolide antibiotic. It works by stopping the growth of bacteria. This helps to reduce inflammation and clear up acne.

Common Side Effects
dronabinol
  • Abdominal pain
  • Dizziness
  • Feeling very happy
  • Nausea
  • Feeling paranoid
erythromycin
  • Peeling
  • Dryness
  • Itching
  • Redness
  • Oily skin
FAERS Reports
dronabinol
  • Nausea 878
  • Fatigue 696
  • Diarrhoea 604
  • Death 593
  • Vomiting 580
erythromycin
  • Drug Hypersensitivity 4,088
  • Nausea 1,271
  • Vomiting 1,121
  • Diarrhoea 1,069
  • Dyspnoea 1,023
Serious Warnings
dronabinol

Dronabinol can cause mental and mood changes. Tell your doctor if you have a history of mental illness. Do not drive or operate heavy machinery until you know how this medicine affects you. This medicine can also affect your heart, causing changes in blood pressure or heart rate. Dronabinol may also increase the risk of seizures.

erythromycin

You should not use this medicine if you are allergic to any of its ingredients.

Pregnancy
dronabinol

Dronabinol may harm your unborn baby. Avoid using this medicine if you are pregnant. If you are breastfeeding and have HIV, do not breastfeed due to the risk of passing HIV to your baby.

erythromycin

It is not known if erythromycin topical solution can harm an unborn baby. Talk to your doctor if you are pregnant or breastfeeding.

Also Compare, Nearby Drugs

How to Read This dronabinol vs erythromycin Comparison

dronabinol is classified in the Cannabinoid Antiemetic drug class, while erythromycin sits within the Macrolide Antibiotic class. Drugs from different classes work through distinct mechanisms, so a head-to-head comparison illustrates trade-offs rather than equivalence. Both drugs are prescription-only, so a licensed provider must authorize use.

Adverse event totals above are pulled from the FDA's Adverse Event Reporting System (FAERS). For these top-ranked reactions alone, dronabinol has 3,351 submissions while erythromycin has 8,572. Those figures reflect cumulative reporting volume, not per-patient risk, so older, widely dispensed drugs typically look worse on count alone. These two drugs have a known minor interaction flagged in FDA labeling, attributed to erythromycin slows down the liver enzymes that process dronabinol, which can cause the drug to stay in your body longer.. Serious warnings, pregnancy guidance, and contraindications can differ even when indications overlap.

A table cannot represent individual circumstances. Data here is sourced from FDA Structured Product Labels (SPL) and FAERS, both of which update as manufacturers and clinicians submit new information. This registry does not provide medical, treatment, substitution, or medication-change directions for dronabinol or erythromycin.

Registry boundary: This comparison displays source-record fields and does not provide individualized medical direction.