dopamine vs selegiline
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Side-by-side comparison of dopamine and selegiline. Data from FDA drug databases (Orange Book, NDC Directory, recalls, shortages) covering 20,000+ approved drugs, plus CMS pricing; see our methodology.
minor Known Drug Interaction
Examples: isocarboxazid, phenelzine, tranylcypromine, rasagiline, selegiline, linezolid.
Intropin
Emsam
Dopamine injection helps improve blood flow in patients suffering from shock. It is used when shock is caused by problems with blood distribution or reduced heart function.
Selegiline is a medicine that can help manage Parkinson's disease. It is used along with levodopa/carbidopa when that medicine is not working as well as it used to.
Dopamine injection is used to improve blood flow in people with shock. Shock can happen when your body isn't getting enough blood flow. This medicine helps to increase blood pressure and improve heart function during these emergencies.
Selegiline is used to help people with Parkinson's disease. It's for those who are already taking levodopa/carbidopa. Selegiline can help when their response to levodopa/carbidopa starts to weaken. It can reduce 'off' time and improve movement.
Dopamine works by stimulating certain receptors in your body. This stimulation helps to increase your heart rate and blood pressure. It also improves blood flow to your kidneys.
Selegiline is a selective MAO-B inhibitor. It works by blocking an enzyme in the brain that breaks down dopamine. This helps to increase the amount of dopamine available, which can improve motor control in Parkinson's disease.
No common side effects listed.
- • Nausea
- • Dizziness
- • Light-headedness
- • Fainting
- • Abdominal pain
- Hypotension 336
- Acute Kidney Injury 182
- Cardiac Arrest 165
- Renal Failure 162
- Condition Aggravated 125
- Insomnia 184
- Application Site Erythema 183
- Dizziness 168
- Hallucination 166
- Fall 137
Dopamine can cause tissue damage if it leaks out of the vein. Tell your doctor right away if you notice any pain, swelling, or redness around the IV site. This medicine may also cause heart rhythm problems. If you have asthma, be aware this drug contains sodium metabisulfite, which can cause a severe allergic reaction.
Taking selegiline with meperidine (Demerol) is dangerous and can cause serious reactions. Also, use caution when taking selegiline with tricyclic antidepressants or selective serotonin reuptake inhibitors (SSRIs) due to the risk of severe toxicity. One patient had a hypertensive crisis when taking selegiline with a sympathomimetic medicine (ephedrine).
There is not enough information about the safety of dopamine during pregnancy. Tell your doctor if you are pregnant or plan to become pregnant. It is not known if dopamine passes into breast milk. Talk to your doctor if you are breastfeeding.
It is not known if selegiline can harm an unborn baby. Talk to your doctor if you are pregnant or plan to become pregnant. It is also not known if selegiline passes into breast milk, so talk to your doctor if you are breastfeeding.
How to Read This dopamine vs selegiline Comparison
dopamine is classified in the Inotropic / Vasopressor drug class, while selegiline sits within the Selective MAO-B Inhibitor class. Drugs from different classes work through distinct mechanisms, so a head-to-head comparison illustrates trade-offs rather than equivalence. Both drugs are prescription-only, so a licensed provider must authorize use.
Adverse event totals above are pulled from the FDA's Adverse Event Reporting System (FAERS). For these top-ranked reactions alone, dopamine has 970 submissions while selegiline has 838. Those figures reflect cumulative reporting volume, not per-patient risk, so older, widely dispensed drugs typically look worse on count alone. These two drugs have a known minor interaction flagged in FDA labeling, attributed to this drug prevents the body from breaking down dopamine, which makes the dopamine much more powerful. this can lead to a severe and rapid increase in blood pressure.. Serious warnings, pregnancy guidance, and contraindications can differ even when indications overlap.
A table cannot represent individual circumstances. Data here is sourced from FDA Structured Product Labels (SPL) and FAERS, both of which update as manufacturers and clinicians submit new information. This registry does not provide medical, treatment, substitution, or medication-change directions for dopamine or selegiline.
Registry boundary: This comparison displays source-record fields and does not provide individualized medical direction.