diazepam vs omeprazole
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Side-by-side comparison of diazepam and omeprazole. Data from FDA drug databases (Orange Book, NDC Directory, recalls, shortages) covering 20,000+ approved drugs, plus CMS pricing; see our methodology.
minor Known Drug Interaction
At present, this reaction is known to occur with cimetidine, ketoconazole, fluvoxamine, fluoxetine, and omeprazole.
Valium
Prilosec
Diazepam (Valium) is a medicine that can help with anxiety, muscle spasms, and seizures. It belongs to a class of drugs called benzodiazepines, which work by slowing down the brain.
Omeprazole (Prilosec) is a medicine that reduces the amount of acid in your stomach. It belongs to a class of drugs called proton pump inhibitors (PPIs).
Diazepam can help manage anxiety disorders or provide short-term relief from anxiety symptoms. It can also relieve symptoms of alcohol withdrawal, such as shaking or agitation. Additionally, diazepam can help with muscle spasms and may be used with other medicines to treat seizures.
This medicine treats frequent heartburn, which is heartburn that occurs 2 or more days a week. It is not meant to give you immediate relief from heartburn. It may take 1 to 4 days for the medicine to fully work.
Diazepam works by increasing the effects of a natural chemical in the brain called GABA. GABA helps to calm the brain and nerves. This can reduce anxiety, relax muscles, and prevent seizures.
Omeprazole works by blocking the production of acid in your stomach. It does this by targeting the cells that make stomach acid. This helps to reduce heartburn symptoms.
- • Drowsiness
- • Fatigue
- • Muscle weakness
- • Uncoordinated movements
- • Headache
- Toxicity To Various Agents 9,167
- Drug Abuse 7,019
- Nausea 6,149
- Fatigue 5,714
- Pain 5,202
- Fatigue 19,901
- Nausea 19,842
- Diarrhoea 19,627
- Dyspnoea 16,336
- Headache 14,629
Diazepam can be habit-forming and can cause serious side effects, including breathing problems, coma, and even death, especially when taken with opioid pain medicines or alcohol. You should not stop taking diazepam suddenly, as this can cause withdrawal symptoms. Talk to your doctor about how to slowly stop taking diazepam.
Children under 18 should ask a doctor before use. Heartburn in children may be a sign of a serious condition.
Diazepam may harm an unborn baby. Talk to your doctor if you are pregnant or plan to become pregnant. It is not known if diazepam passes into breast milk, so talk to your doctor before breastfeeding.
Talk to your doctor if you are pregnant or breastfeeding before taking this medicine. It is important to weigh the benefits and risks with your doctor.
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How to Read This diazepam vs omeprazole Comparison
diazepam is classified in the Benzodiazepine drug class, while omeprazole sits within the Proton Pump Inhibitor (PPI) class. Drugs from different classes work through distinct mechanisms, so a head-to-head comparison illustrates trade-offs rather than equivalence. Both drugs are split between OTC and prescription status, which affects access and supervision.
Adverse event totals above are pulled from the FDA's Adverse Event Reporting System (FAERS). For these top-ranked reactions alone, diazepam has 33,251 submissions while omeprazole has 90,335. Those figures reflect cumulative reporting volume, not per-patient risk, so older, widely dispensed drugs typically look worse on count alone. These two drugs have a known minor interaction flagged in FDA labeling, attributed to omeprazole slows down the liver's ability to process diazepam. this can lead to higher levels of the drug in your body.. Serious warnings, pregnancy guidance, and contraindications can differ even when indications overlap.
A table cannot represent individual circumstances. Data here is sourced from FDA Structured Product Labels (SPL) and FAERS, both of which update as manufacturers and clinicians submit new information. This registry does not provide medical, treatment, substitution, or medication-change directions for diazepam or omeprazole.
Registry boundary: This comparison displays source-record fields and does not provide individualized medical direction.