diazepam vs ketoconazole
Side-by-side comparison of diazepam and ketoconazole. Data from FDA drug databases (Orange Book, NDC Directory, recalls, shortages) covering 20,000+ approved drugs, plus CMS pricing; see our methodology.
minor Known Drug Interaction
At present, this reaction is known to occur with cimetidine, ketoconazole, fluvoxamine, fluoxetine, and omeprazole.
Recommendation: Tell your doctor if you feel overly tired, as they may need to lower your diazepam dose.
Valium
Nizoral
Diazepam (Valium) is a medicine that can help with anxiety, muscle spasms, and seizures. It belongs to a class of drugs called benzodiazepines, which work by slowing down the brain.
Ketoconazole shampoo is an antifungal medicine. It treats a fungal infection on your skin.
Diazepam can help manage anxiety disorders or provide short-term relief from anxiety symptoms. It can also relieve symptoms of alcohol withdrawal, such as shaking or agitation. Additionally, diazepam can help with muscle spasms and may be used with other medicines to treat seizures.
This shampoo treats tinea versicolor, a fungal infection. This infection can cause patches on your skin that are lighter or darker than the surrounding skin. These patches may appear on your trunk, neck, arms, and upper thighs.
Diazepam works by increasing the effects of a natural chemical in the brain called GABA. GABA helps to calm the brain and nerves. This can reduce anxiety, relax muscles, and prevent seizures.
Ketoconazole is an antifungal medicine. It works by stopping the growth of the fungus. This helps to clear up the infection.
- • Drowsiness
- • Fatigue
- • Muscle weakness
- • Uncoordinated movements
No common side effects listed.
- Harm from certain substances 9,167
- Misuse of medicine 7,019
- Feeling sick to your stomach 6,144
- Feeling tired 5,714
- Discomfort 5,202
- Feeling tired 929
- Itching 902
- Feeling sick to your stomach 834
- Skin breakout 802
- Loose stool 760
Diazepam can be habit-forming and can cause serious side effects, including breathing problems, coma, and even death, especially when taken with opioid pain medicines or alcohol. You should not stop taking diazepam suddenly, as this can cause withdrawal symptoms. Talk to your doctor about how to slowly stop taking diazepam.
You should not use this shampoo if you are allergic to ketoconazole or any of the other ingredients.
Diazepam may harm an unborn baby. Talk to your doctor if you are pregnant or plan to become pregnant. It is not known if diazepam passes into breast milk, so talk to your doctor before breastfeeding.
It is not known if ketoconazole shampoo can harm an unborn baby. Talk to your doctor if you are pregnant or breastfeeding before using this medicine.
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How to Read This diazepam vs ketoconazole Comparison
diazepam is classified in the Benzodiazepine drug class, while ketoconazole sits within the Azole Antifungal class. Drugs from different classes work through distinct mechanisms, so a head-to-head comparison illustrates trade-offs rather than equivalence. Both drugs are split between OTC and prescription status, which affects access and supervision.
Adverse event totals above are pulled from the FDA's Adverse Event Reporting System (FAERS). For these top-ranked reactions alone, diazepam has 33,246 submissions while ketoconazole has 4,227. Those figures reflect cumulative reporting volume, not per-patient risk, so older, widely dispensed drugs typically look worse on count alone. These two drugs have a known minor interaction flagged in FDA labeling, attributed to ketoconazole stops the body from breaking down diazepam normally. this can cause diazepam to build up in your system.. Serious warnings, pregnancy guidance, and contraindications can differ even when indications overlap.
A table cannot substitute for clinical judgment. Effectiveness, tolerability, drug-drug interactions with your other medications, kidney and liver function, pregnancy status, insurance formulary, and price all feed into a decision that only a licensed prescriber can make responsibly. Data here is sourced from FDA Structured Product Labels (SPL) and FAERS, both of which update as manufacturers and clinicians submit new information. This page is for educational purposes only, is not medical advice, and should not be used to self-switch between diazepam and ketoconazole - always consult your physician or pharmacist first.
Important: This comparison is for informational purposes only. Drug effects vary between individuals. Always consult your doctor or pharmacist for personalized medical advice.