darunavir vs mometasone

According to this portal's Publishing Organization, this page was last reviewed in August 2026 against our methodology. Figures and extracts on this site, including tables above 1,000 rows when the corpus is that large, are the publisher's responsibility.

Side-by-side comparison of darunavir and mometasone. Data from FDA drug databases (Orange Book, NDC Directory, recalls, shortages) covering 20,000+ approved drugs, plus CMS pricing; see our methodology.

moderate Known Drug Interaction

betamethasone budesonide ciclesonide fluticasone methylprednisolone mometasone triamcinolone ↑ corticosteroids Co-administration with corticosteroids (all routes of administration) of which exposures are significantly increased by strong CYP3A inhibitors can increase the risk for Cushing's syndrome and adrenal suppression.

Drug Class
darunavir HIV Protease Inhibitor
mometasone Inhaled Corticosteroid
Type
darunavir Prescription
mometasone Prescription
Summary
darunavir

Darunavir is a medicine used to treat HIV. It belongs to a class of drugs called protease inhibitors and must be taken with ritonavir.

mometasone

Mometasone cream is a medicine that reduces skin inflammation and itching. It belongs to a class of drugs called corticosteroids.

What It Treats
darunavir

Darunavir is used to treat HIV-1 infection in adults and children 3 years and older. It must be taken with ritonavir and other HIV medicines. Darunavir helps to lower the amount of HIV in your body.

mometasone

This cream treats skin problems that cause inflammation and itching. It can be used for skin conditions that respond to corticosteroids. It is for use on people 2 years and older.

How It Works
darunavir

Darunavir is a protease inhibitor. It works by blocking an enzyme called protease that HIV needs to make copies of itself. This helps to slow down the spread of HIV in your body.

mometasone

Mometasone is a corticosteroid that reduces inflammation. It works by reducing the chemicals in the body that cause swelling and itching. This helps to relieve skin irritation.

Common Side Effects
darunavir
  • Diarrhea
  • Nausea
  • Rash
  • Headache
  • Abdominal pain
mometasone
  • Burning
  • Itching
  • Skin thinning
FAERS Reports
darunavir
  • Foetal Exposure During Pregnancy 1,150
  • Drug Interaction 981
  • Pain 889
  • Emotional Distress 812
  • Anxiety 811
mometasone
  • Dyspnoea 1,730
  • Asthma 1,553
  • Headache 1,393
  • Cough 1,178
  • Fatigue 1,098
Serious Warnings
darunavir

Darunavir can cause liver problems. Your doctor should check your liver before you start taking darunavir and during treatment. Tell your doctor right away if you have any signs of liver problems, such as yellowing of the skin or eyes.

mometasone

Using too much mometasone cream, using it for a long time, or covering large areas of skin can increase the risk of side effects. This can cause your body to stop making enough of its own natural steroid hormones. Children are more likely to get these side effects. This medicine may also increase your risk of cataracts and glaucoma. Tell your doctor if you have blurred vision.

Pregnancy
darunavir

Tell your doctor if you are pregnant or plan to become pregnant. The recommended dose during pregnancy is 600 mg twice daily with ritonavir 100mg and food. Women with HIV should not breastfeed because HIV can be passed to the baby through breast milk.

mometasone

If you are pregnant, use mometasone cream only if your doctor says it is okay. There may be risks to the baby. It is not known if mometasone passes into breast milk, so talk to your doctor before using it if you are breastfeeding.

Also Compare, Nearby Drugs

How to Read This darunavir vs mometasone Comparison

darunavir is classified in the HIV Protease Inhibitor drug class, while mometasone sits within the Inhaled Corticosteroid class. Drugs from different classes work through distinct mechanisms, so a head-to-head comparison illustrates trade-offs rather than equivalence. Both drugs are prescription-only, so a licensed provider must authorize use.

Adverse event totals above are pulled from the FDA's Adverse Event Reporting System (FAERS). For these top-ranked reactions alone, darunavir has 4,643 submissions while mometasone has 6,952. Those figures reflect cumulative reporting volume, not per-patient risk, so older, widely dispensed drugs typically look worse on count alone. These two drugs have a known moderate interaction flagged in FDA labeling, attributed to darunavir slows down how fast your body gets rid of mometasone, which can cause the steroid to reach dangerously high levels.. Serious warnings, pregnancy guidance, and contraindications can differ even when indications overlap.

A table cannot represent individual circumstances. Data here is sourced from FDA Structured Product Labels (SPL) and FAERS, both of which update as manufacturers and clinicians submit new information. This registry does not provide medical, treatment, substitution, or medication-change directions for darunavir or mometasone.

Registry boundary: This comparison displays source-record fields and does not provide individualized medical direction.