cyclosporine vs metoclopramide
According to this portal's Publishing Organization, this page was last reviewed in August 2026 against our methodology. Figures and extracts on this site, including tables above 1,000 rows when the corpus is that large, are the publisher's responsibility.
Side-by-side comparison of cyclosporine and metoclopramide. Data from FDA drug databases (Orange Book, NDC Directory, recalls, shortages) covering 20,000+ approved drugs, plus CMS pricing; see our methodology.
minor Known Drug Interaction
digoxin) by metoclopramide, whereas the rate and/or extent of absorption of drugs from the small bowel may be increased (e.g., acetaminophen, tetracycline, levodopa, ethanol, cyclosporine).
Neoral, Sandimmune, Restasis
Reglan
Vevye eye drops contain cyclosporine. They help treat the signs and symptoms of dry eye disease.
Metoclopramide is a drug that helps with stomach problems. It can help food move faster through your stomach and reduce nausea.
Vevye treats the signs and symptoms of dry eye disease. Dry eye can cause discomfort, stinging, and blurred vision. This medicine can help reduce these symptoms.
This medicine treats heartburn caused by acid reflux when other treatments don't work. It also helps with symptoms of slow stomach emptying in people with diabetes, like nausea, vomiting, and feeling full. This medicine is for adults and should not be used for more than 12 weeks.
Vevye contains cyclosporine, which is an immunosuppressant. It works by decreasing inflammation in the eyes. This helps your eyes make more tears.
Metoclopramide helps your stomach muscles move faster. This helps food empty from your stomach more quickly. It also blocks a chemical in your brain that causes nausea.
- • Irritation where the drops are applied (8%)
- • Restlessness
- • Drowsiness
- • Fatigue
- • Feeling tired
- Eye Irritation 7,786
- Pyrexia 4,064
- Eye Pain 3,808
- Nausea 3,623
- Diarrhoea 3,562
- Tardive Dyskinesia 13,205
- Extrapyramidal Disorder 11,628
- Nervous System Disorder 7,175
- Dystonia 6,661
- Pain 4,666
To avoid eye injury or contamination, do not touch the bottle tip to your eye or any other surface. Do not use Vevye while wearing contact lenses. If you wear contacts, remove them before using the drops. You can put them back in 15 minutes after using Vevye.
Metoclopramide can cause a serious movement disorder called tardive dyskinesia. This may not go away even after you stop taking the medicine. The risk of tardive dyskinesia increases with long-term use and high doses. Call your doctor right away if you have uncontrolled muscle movements.
It is not known if Vevye will harm an unborn baby. Talk to your doctor if you are pregnant or plan to become pregnant. Cyclosporine can pass into breast milk after being taken orally, but it is unknown if it passes into breast milk from eye drops. Talk to your doctor if you are breastfeeding.
Tell your doctor if you are pregnant or plan to become pregnant. It is not known if this medicine will harm your unborn baby. Talk to your doctor about the risks and benefits of taking this medicine while breastfeeding.
How to Read This cyclosporine vs metoclopramide Comparison
cyclosporine is classified in the Calcineurin Inhibitor (Immunosuppressant) drug class, while metoclopramide sits within the Prokinetic / Antiemetic class. Drugs from different classes work through distinct mechanisms, so a head-to-head comparison illustrates trade-offs rather than equivalence. Both drugs are prescription-only, so a licensed provider must authorize use.
Adverse event totals above are pulled from the FDA's Adverse Event Reporting System (FAERS). For these top-ranked reactions alone, cyclosporine has 22,843 submissions while metoclopramide has 43,335. Those figures reflect cumulative reporting volume, not per-patient risk, so older, widely dispensed drugs typically look worse on count alone. These two drugs have a known minor interaction flagged in FDA labeling, attributed to metoclopramide speeds up how fast the stomach empties, which causes the body to absorb cyclosporine more quickly or in larger amounts.. Serious warnings, pregnancy guidance, and contraindications can differ even when indications overlap.
A table cannot represent individual circumstances. Data here is sourced from FDA Structured Product Labels (SPL) and FAERS, both of which update as manufacturers and clinicians submit new information. This registry does not provide medical, treatment, substitution, or medication-change directions for cyclosporine or metoclopramide.
Registry boundary: This comparison displays source-record fields and does not provide individualized medical direction.