clobazam vs omeprazole
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Side-by-side comparison of clobazam and omeprazole. Data from FDA drug databases (Orange Book, NDC Directory, recalls, shortages) covering 20,000+ approved drugs, plus CMS pricing; see our methodology.
minor Known Drug Interaction
Dosage adjustment of clobazam oral suspension may be necessary when co-administered with strong CYP2C19 inhibitors (e.g., fluconazole, fluvoxamine, ticlopidine) or moderate CYP2C19 inhibitors (e.g., omeprazole) [see Clinical Pharmacology ( 12.3 )].
Onfi, Sympazan
Prilosec
Clobazam oral suspension is a medicine used with other medicines to treat seizures caused by Lennox-Gastaut syndrome. It is a type of drug called a benzodiazepine.
Omeprazole (Prilosec) is a medicine that reduces the amount of acid in your stomach. It belongs to a class of drugs called proton pump inhibitors (PPIs).
Clobazam oral suspension is used to treat seizures in people 2 years and older who have Lennox-Gastaut syndrome (LGS). LGS is a severe form of epilepsy that begins in childhood. This medicine helps to control seizures when used with other seizure medicines.
This medicine treats frequent heartburn, which is heartburn that occurs 2 or more days a week. It is not meant to give you immediate relief from heartburn. It may take 1 to 4 days for the medicine to fully work.
Clobazam belongs to a class of drugs called benzodiazepines. It works by affecting certain chemicals in the brain that may be unbalanced in people with seizures. This helps to reduce the frequency of seizures.
Omeprazole works by blocking the production of acid in your stomach. It does this by targeting the cells that make stomach acid. This helps to reduce heartburn symptoms.
- • Constipation
- • Sleepiness or drowsiness
- • Fever
- • Sluggishness
- • Drooling
- • Headache
- Seizure 4,619
- Somnolence 1,798
- Drug Interaction 1,123
- Fatigue 1,090
- Epilepsy 805
- Fatigue 19,901
- Nausea 19,842
- Diarrhoea 19,627
- Dyspnoea 16,336
- Headache 14,629
Clobazam can cause serious side effects: * **Risk of Using with Opioids:** Taking clobazam with opioid medicines can cause severe sleepiness, slowed breathing, coma, and death. Only take them together if no other treatment works, and use the lowest dose for the shortest time. * **Risk of Abuse, Misuse, and Addiction:** Clobazam can be abused, misused, and lead to addiction, overdose or death. Your doctor will assess your risk before and during treatment. * **Risk of Dependence and Withdrawal:** Taking clobazam can lead to physical dependence. Stopping it suddenly can cause life-threatening withdrawal symptoms. To stop, your doctor will slowly lower your dose.
Children under 18 should ask a doctor before use. Heartburn in children may be a sign of a serious condition.
Clobazam may harm your unborn baby. If you are pregnant or plan to become pregnant, talk to your doctor. There is a pregnancy registry for women who take anti-epilepsy drugs like clobazam. You can enroll by calling 1-888-233-2334.
Talk to your doctor if you are pregnant or breastfeeding before taking this medicine. It is important to weigh the benefits and risks with your doctor.
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How to Read This clobazam vs omeprazole Comparison
clobazam is classified in the Benzodiazepine (Anticonvulsant) drug class, while omeprazole sits within the Proton Pump Inhibitor (PPI) class. Drugs from different classes work through distinct mechanisms, so a head-to-head comparison illustrates trade-offs rather than equivalence. Both drugs are split between OTC and prescription status, which affects access and supervision.
Adverse event totals above are pulled from the FDA's Adverse Event Reporting System (FAERS). For these top-ranked reactions alone, clobazam has 9,435 submissions while omeprazole has 90,335. Those figures reflect cumulative reporting volume, not per-patient risk, so older, widely dispensed drugs typically look worse on count alone. These two drugs have a known minor interaction flagged in FDA labeling, attributed to omeprazole slows down the liver's ability to process clobazam. this can cause the amount of clobazam in your body to rise to higher levels.. Serious warnings, pregnancy guidance, and contraindications can differ even when indications overlap.
A table cannot represent individual circumstances. Data here is sourced from FDA Structured Product Labels (SPL) and FAERS, both of which update as manufacturers and clinicians submit new information. This registry does not provide medical, treatment, substitution, or medication-change directions for clobazam or omeprazole.
Registry boundary: This comparison displays source-record fields and does not provide individualized medical direction.