clarithromycin vs lorazepam
Side-by-side comparison of clarithromycin and lorazepam. Data from FDA drug databases (Orange Book, NDC Directory, recalls, shortages) covering 20,000+ approved drugs, plus CMS pricing; see our methodology.
minor Known Drug Interaction
Temazepam Nitrazepam Lorazepam No Dose Adjustment Temazepam, Nitrazepam, Lorazepam: For benzodiazepines which are not metabolized by CYP3A (e.g., temazepam, nitrazepam, lorazepam), a clinically important interaction with clarithromycin is unlikely.
Recommendation: No special dose changes are usually needed for this combination. You can take these medications together as prescribed by your doctor.
Biaxin
Ativan
Clarithromycin is an antibiotic that fights bacterial infections. It belongs to a class of drugs called macrolides.
Lorazepam is a medicine that can help with anxiety. It belongs to a class of drugs called benzodiazepines, which slow down activity in the brain.
Clarithromycin treats mild to moderate infections caused by certain bacteria. It can treat bronchitis, sinus infections, pneumonia, and throat/tonsil infections. It also treats skin infections, ear infections in children, certain mycobacterial infections, and H. pylori infections that cause ulcers.
Lorazepam is used to manage anxiety disorders. It can also provide short-term relief from anxiety symptoms or anxiety linked to depression. However, it is not for the stress of everyday life. Talk to your doctor regularly to see if you still need this medicine.
Clarithromycin works by stopping the growth of bacteria. It prevents bacteria from making proteins they need to survive. This helps your body fight off the infection.
Lorazepam works by affecting certain chemicals in your brain. It enhances the effects of a natural brain chemical called GABA. This helps to calm your nerves and reduce anxiety.
- • Abdominal pain
- • Diarrhea
- • Nausea
- • Vomiting
- • Taste changes
- • Feeling sleepy or drowsy
- • Dizziness
- Drug Interaction 2,906
- Nausea 2,214
- Dyspnoea 1,959
- Diarrhoea 1,937
- Malaise 1,650
- Tiredness 13,458
- Feeling sick to your stomach 13,333
- Loose stools 10,352
- Difficulty breathing 9,234
- Feeling worried or nervous 8,840
Clarithromycin can cause severe allergic reactions. Stop taking it and get medical help right away if you have signs of a reaction. This medicine can also cause heart rhythm problems (QT prolongation) and liver problems. Tell your doctor if you have heart or liver issues. Clarithromycin may increase the risk of death in patients with coronary artery disease.
Taking lorazepam with opioid medicines can cause very serious problems, including slowed or shallow breathing, coma, and death. Only take them together if there are no other options. Lorazepam can be habit-forming, leading to abuse, misuse, and addiction, which can result in overdose or death. Using lorazepam for a long time can cause you to become dependent on it. Stopping it suddenly can cause dangerous withdrawal symptoms. Your doctor will slowly lower your dose to prevent withdrawal.
Clarithromycin is not recommended during pregnancy unless there are no other options. Talk to your doctor if you are pregnant or plan to become pregnant. It is not known if clarithromycin passes into breast milk, so talk to your doctor before breastfeeding.
Lorazepam may harm an unborn baby. Talk to your doctor if you are pregnant, plan to become pregnant, or are breastfeeding while taking this medicine. It can pass into breast milk and affect the baby.
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How to Read This clarithromycin vs lorazepam Comparison
clarithromycin is classified in the Macrolide Antibiotic drug class, while lorazepam sits within the Benzodiazepine class. Drugs from different classes work through distinct mechanisms, so a head-to-head comparison illustrates trade-offs rather than equivalence. Both drugs are prescription-only, so a licensed provider must authorize use.
Adverse event totals above are pulled from the FDA's Adverse Event Reporting System (FAERS). For these top-ranked reactions alone, clarithromycin has 10,666 submissions while lorazepam has 55,217. Those figures reflect cumulative reporting volume, not per-patient risk, so older, widely dispensed drugs typically look worse on count alone. These two drugs have a known minor interaction flagged in FDA labeling, attributed to lorazepam is processed by the body in a way that is not affected by clarithromycin. because of this, these two drugs are not expected to interfere with each other.. Serious warnings, pregnancy guidance, and contraindications can differ even when indications overlap.
A table cannot substitute for clinical judgment. Effectiveness, tolerability, drug-drug interactions with your other medications, kidney and liver function, pregnancy status, insurance formulary, and price all feed into a decision that only a licensed prescriber can make responsibly. Data here is sourced from FDA Structured Product Labels (SPL) and FAERS, both of which update as manufacturers and clinicians submit new information. This page is for educational purposes only, is not medical advice, and should not be used to self-switch between clarithromycin and lorazepam - always consult your physician or pharmacist first.
Important: This comparison is for informational purposes only. Drug effects vary between individuals. Always consult your doctor or pharmacist for personalized medical advice.