clarithromycin vs dabigatran
PlainMeds reviewed this comparison against our methodology in August 2026. It places FDA and CMS record fields side by side, without recommending either medication.
Side-by-side comparison of clarithromycin and dabigatran. Data from FDA drug databases (Orange Book, NDC Directory, recalls, shortages) covering 20,000+ approved drugs, plus CMS pricing; see our methodology.
minor Known Drug Interaction
The use of the P-gp inhibitors verapamil, amiodarone, quinidine, clarithromycin, and ticagrelor does not require a dosage adjustment of dabigatran etexilate.
Biaxin
Pradaxa
Clarithromycin is an antibiotic that fights bacterial infections. It belongs to a class of drugs called macrolides.
Dabigatran (Pradaxa) is a drug that helps to prevent blood clots from forming. It is used to lower the risk of stroke and treat or prevent other dangerous clots in your body.
Clarithromycin treats mild to moderate infections caused by certain bacteria. It can treat bronchitis, sinus infections, pneumonia, and throat/tonsil infections. It also treats skin infections, ear infections in children, certain mycobacterial infections, and H. pylori infections that cause ulcers.
This medicine can help prevent strokes in people with an irregular heartbeat called atrial fibrillation. It can also treat blood clots in your legs (deep vein thrombosis or DVT) or lungs (pulmonary embolism or PE). Dabigatran can also lower the risk of these clots coming back. It is also used to prevent blood clots after hip replacement surgery.
Clarithromycin works by stopping the growth of bacteria. It prevents bacteria from making proteins they need to survive. This helps your body fight off the infection.
Dabigatran is a direct thrombin inhibitor. Thrombin is a substance in the blood that helps clots form. By blocking thrombin, dabigatran helps to keep your blood from clotting too easily.
- • Abdominal pain
- • Diarrhea
- • Nausea
- • Vomiting
- • Taste changes
- • Upset stomach
- • Bleeding more easily (such as nosebleeds or heavier periods)
- Drug Interaction 2,906
- Nausea 2,214
- Dyspnoea 1,959
- Diarrhoea 1,937
- Malaise 1,650
No adverse event reports.
Clarithromycin can cause severe allergic reactions. Stop taking it and get medical help right away if you have signs of a reaction. This medicine can also cause heart rhythm problems (QT prolongation) and liver problems. Tell your doctor if you have heart or liver issues. Clarithromycin may increase the risk of death in patients with coronary artery disease.
Dabigatran has two important warnings. First, stopping this medicine too early can raise your risk of blood clots. Do not stop taking it without talking to your doctor. Second, this medicine can cause bleeding around the spine if you get an epidural or spinal tap. This can lead to paralysis. Tell your doctor if you are going to have any spinal procedures.
Clarithromycin is not recommended during pregnancy unless there are no other options. Talk to your doctor if you are pregnant or plan to become pregnant. It is not known if clarithromycin passes into breast milk, so talk to your doctor before breastfeeding.
Talk to your doctor if you are pregnant or plan to become pregnant. Dabigatran may increase the risk of bleeding in the fetus. Breastfeeding is not recommended while taking this medicine.
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How to Read This clarithromycin vs dabigatran Comparison
clarithromycin is classified in the Macrolide Antibiotic drug class, while dabigatran sits within the Direct Thrombin Inhibitor class. Drugs from different classes work through distinct mechanisms, so a head-to-head comparison illustrates trade-offs rather than equivalence. Both drugs are prescription-only, so a licensed provider must authorize use.
Adverse event totals above are pulled from the FDA's Adverse Event Reporting System (FAERS). For these top-ranked reactions alone, clarithromycin has 10,666 submissions while dabigatran has 0. Those figures reflect cumulative reporting volume, not per-patient risk, so older, widely dispensed drugs typically look worse on count alone. These two drugs have a known minor interaction flagged in FDA labeling, attributed to clarithromycin affects a protein that moves dabigatran, but the change is too small to affect how the medicine works in your body.. Serious warnings, pregnancy guidance, and contraindications can differ even when indications overlap.
A table cannot represent individual circumstances. Data here is sourced from FDA Structured Product Labels (SPL) and FAERS, both of which update as manufacturers and clinicians submit new information. This registry does not provide medical, treatment, substitution, or medication-change directions for clarithromycin or dabigatran.
Registry boundary: This comparison displays source-record fields and does not provide individualized medical direction.