carbidopa/levodopa vs erythromycin

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Side-by-side comparison of carbidopa/levodopa and erythromycin. Data from FDA drug databases (Orange Book, NDC Directory, recalls, shortages) covering 20,000+ approved drugs, plus CMS pricing; see our methodology.

minor Known Drug Interaction

These include probenecid, cholestyramine, and some antibiotics (e.g., erythromycin, rifampicin, ampicillin and chloramphenicol).

Drug Class
carbidopa/levodopa Dopamine Precursor Combination
erythromycin Macrolide Antibiotic
Type
carbidopa/levodopa Prescription
erythromycin Prescription
Summary
carbidopa/levodopa

This medicine contains carbidopa, levodopa, and entacapone. It is used to treat Parkinson's disease.

erythromycin

Erythromycin Topical Solution is a medicine that you put on your skin to treat acne. It contains an antibiotic to help clear up your skin.

What It Treats
carbidopa/levodopa

This medicine treats Parkinson's disease. It can help when other medicines stop working as well near the end of a dose. It can also replace other medicines containing similar ingredients.

erythromycin

Erythromycin Topical Solution treats acne vulgaris. This medicine helps to reduce acne on your face, neck, shoulders, chest, and back. It works by fighting the bacteria that cause acne.

How It Works
carbidopa/levodopa

Levodopa turns into dopamine in your brain, helping to control movement. Carbidopa helps levodopa get to your brain. Entacapone helps levodopa work longer.

erythromycin

Erythromycin is a macrolide antibiotic. It works by stopping the growth of bacteria. This helps to reduce inflammation and clear up acne.

Common Side Effects
carbidopa/levodopa
  • Uncontrolled movements
  • Diarrhea
  • Nausea
  • Belly pain
  • Vomiting
erythromycin
  • Peeling
  • Dryness
  • Itching
  • Redness
  • Oily skin
FAERS Reports
carbidopa/levodopa
  • Fall 4,293
  • Seeing or hearing things that are not there 3,733
  • Shaking 3,257
  • Uncontrolled movements 2,903
  • Death 2,727
erythromycin
  • Drug Hypersensitivity 4,088
  • Nausea 1,271
  • Vomiting 1,121
  • Diarrhoea 1,069
  • Dyspnoea 1,023
Serious Warnings
carbidopa/levodopa

This medicine can make you fall asleep suddenly, even when you feel awake. Be careful when driving or doing other activities where you need to be alert. Stopping this medicine suddenly can cause serious problems like fever and confusion.

erythromycin

You should not use this medicine if you are allergic to any of its ingredients.

Pregnancy
carbidopa/levodopa

This medicine may harm your unborn baby. Talk to your doctor if you are pregnant or plan to become pregnant. It is not known if this medicine passes into breast milk.

erythromycin

It is not known if erythromycin topical solution can harm an unborn baby. Talk to your doctor if you are pregnant or breastfeeding.

Also Compare, Nearby Drugs

How to Read This carbidopa/levodopa vs erythromycin Comparison

carbidopa/levodopa is classified in the Dopamine Precursor Combination drug class, while erythromycin sits within the Macrolide Antibiotic class. Drugs from different classes work through distinct mechanisms, so a head-to-head comparison illustrates trade-offs rather than equivalence. Both drugs are prescription-only, so a licensed provider must authorize use.

Adverse event totals above are pulled from the FDA's Adverse Event Reporting System (FAERS). For these top-ranked reactions alone, carbidopa/levodopa has 16,913 submissions while erythromycin has 8,572. Those figures reflect cumulative reporting volume, not per-patient risk, so older, widely dispensed drugs typically look worse on count alone. These two drugs have a known minor interaction flagged in FDA labeling, attributed to this antibiotic can change how your body processes levodopa, which might affect the amount of medicine that gets into your blood.. Serious warnings, pregnancy guidance, and contraindications can differ even when indications overlap.

A table cannot represent individual circumstances. Data here is sourced from FDA Structured Product Labels (SPL) and FAERS, both of which update as manufacturers and clinicians submit new information. This registry does not provide medical, treatment, substitution, or medication-change directions for carbidopa/levodopa or erythromycin.

Registry boundary: This comparison displays source-record fields and does not provide individualized medical direction.