carbamazepine vs rivaroxaban
Side-by-side comparison of carbamazepine and rivaroxaban. Data from FDA drug databases (Orange Book, NDC Directory, recalls, shortages) covering 20,000+ approved drugs, plus CMS pricing; see our methodology.
moderate Known Drug Interaction
7.3 Drugs that Induce Cytochrome P450 3A Enzymes and Drug Transport Systems Avoid concomitant use of XARELTO with drugs that are combined P-gp and strong CYP3A inducers (e.g., carbamazepine, phenytoin, rifampin, St.
Recommendation: Avoid taking these drugs together to ensure your blood thinner stays at the right level in your body.
Tegretol
Xarelto
Carbamazepine is a medicine used to control seizures and treat nerve pain. It works by reducing abnormal electrical activity in the brain and calming nerve signals.
Rivaroxaban (Xarelto) is a drug that helps to prevent blood clots from forming. It is used to lower the risk of stroke and treat or prevent dangerous clots in your veins and lungs.
Carbamazepine is used to treat certain types of seizures, including partial seizures and generalized tonic-clonic seizures. It can also treat mixed seizure patterns. Carbamazepine also treats the pain from trigeminal neuralgia, a nerve disorder that causes intense facial pain. It is also sometimes used for glossopharyngeal neuralgia.
This medicine can help prevent strokes in people with an irregular heartbeat called atrial fibrillation. It also treats blood clots in the legs (deep vein thrombosis or DVT) and lungs (pulmonary embolism or PE). Rivaroxaban can also lower the risk of these clots coming back. It is also used to prevent blood clots after hip or knee replacement surgery and in acutely ill patients.
Carbamazepine is an anticonvulsant. It works by reducing the spread of seizure activity in the brain. It also stabilizes nerve impulses to reduce pain.
Rivaroxaban is a factor Xa inhibitor. It blocks a substance in your blood called factor Xa. By blocking factor Xa, the medicine helps to prevent blood clots from forming.
- • Dizziness
- • Drowsiness
- • Unsteadiness
- • Nausea
- • Vomiting
- • Bleeding
- • Cough
- • Vomiting
- • Gastroenteritis (inflammation of the stomach and intestines)
- Seizure 3,609
- Interaction with another medicine 3,369
- Fall 3,044
- Dizziness 2,860
- Fever 2,690
- Bleeding in the stomach or intestines 21,559
- Bleeding 7,713
- Shortness of breath 7,149
- Nosebleed 6,698
- Tiredness 6,546
Carbamazepine can cause severe skin reactions, including Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN), which can be fatal. If you are of Asian descent, you may need a blood test before starting this medicine. Carbamazepine can also cause serious blood problems like aplastic anemia and agranulocytosis. Contact your doctor right away if you develop a fever, sore throat, rash, or unusual bleeding or bruising.
This medicine has two important warnings. First, stopping this medicine too early can increase your risk of blood clots. Do not stop taking it without talking to your doctor first. Second, if you receive spinal anesthesia or have a spinal puncture while taking this medicine, you have a risk of a blood clot forming around your spine, which can cause long-term paralysis.
Carbamazepine may harm an unborn baby. Talk to your doctor if you are pregnant or plan to become pregnant. It is not known if carbamazepine passes into breast milk, so talk to your doctor about breastfeeding.
Talk to your doctor if you are pregnant or plan to become pregnant. This medicine may cause bleeding problems during pregnancy and delivery. It is not known if this medicine passes into breast milk, so talk to your doctor about the risks and benefits of breastfeeding.
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How to Read This carbamazepine vs rivaroxaban Comparison
carbamazepine is classified in the Anticonvulsant drug class, while rivaroxaban sits within the Direct Oral Anticoagulant (Factor Xa Inhibitor) class. Drugs from different classes work through distinct mechanisms, so a head-to-head comparison illustrates trade-offs rather than equivalence. Both drugs are prescription-only, so a licensed provider must authorize use.
Adverse event totals above are pulled from the FDA's Adverse Event Reporting System (FAERS). For these top-ranked reactions alone, carbamazepine has 15,572 submissions while rivaroxaban has 49,665. Those figures reflect cumulative reporting volume, not per-patient risk, so older, widely dispensed drugs typically look worse on count alone. These two drugs have a known moderate interaction flagged in FDA labeling, attributed to carbamazepine causes your body to process rivaroxaban too quickly, which may prevent the drug from protecting you against blood clots.. Serious warnings, pregnancy guidance, and contraindications can differ even when indications overlap.
A table cannot substitute for clinical judgment. Effectiveness, tolerability, drug-drug interactions with your other medications, kidney and liver function, pregnancy status, insurance formulary, and price all feed into a decision that only a licensed prescriber can make responsibly. Data here is sourced from FDA Structured Product Labels (SPL) and FAERS, both of which update as manufacturers and clinicians submit new information. This page is for educational purposes only, is not medical advice, and should not be used to self-switch between carbamazepine and rivaroxaban - always consult your physician or pharmacist first.
Important: This comparison is for informational purposes only. Drug effects vary between individuals. Always consult your doctor or pharmacist for personalized medical advice.