buspirone vs levomilnacipran
Side-by-side comparison of buspirone and levomilnacipran. Data from FDA drug databases (Orange Book, NDC Directory, recalls, shortages) covering 20,000+ approved drugs, plus CMS pricing; see our methodology.
minor Known Drug Interaction
Examples: other SNRIs, SSRIs, triptans, tricyclic antidepressants, opioids, lithium, buspirone, amphetamines, tryptophan, and St.
Recommendation: Your doctor should monitor you closely for signs of too much serotonin, such as shivering, sweating, or confusion. Tell your provider immediately if you feel unusual.
BuSpar
Fetzima
Buspirone is a medicine that can help manage anxiety disorders. It can also provide short-term relief from anxiety symptoms.
Fetzima is a medicine used to treat major depressive disorder (MDD) in adults. It helps to improve your mood by affecting certain chemicals in the brain.
Buspirone is used to manage anxiety disorders. It can also help relieve anxiety symptoms for a short time. This medicine is often used for Generalized Anxiety Disorder (GAD), which involves constant worry and tension.
Fetzima is used to treat major depressive disorder (MDD) in adults. MDD can cause you to feel sad, lose interest in activities, and have trouble with daily life. Fetzima can help improve your mood and reduce these symptoms.
Buspirone affects certain chemicals in your brain that may be unbalanced. This helps to reduce anxiety. It is different from other anxiety medicines like benzodiazepines.
Fetzima is a type of drug called a serotonin-norepinephrine reuptake inhibitor (SNRI). It works by increasing the levels of serotonin and norepinephrine in your brain. These chemicals can help improve your mood and reduce symptoms of depression.
- • Dizziness
- • Nausea
- • Headache
- • Nervousness
- • Lightheadedness
- • Nausea
- • Constipation
- • Increased sweating
- • Increased heart rate
- • Erectile dysfunction
- Tiredness 759
- Feeling sick to your stomach 744
- Head pain 675
- Worry 636
- Aches 541
- Pain 210
- Throwing up 208
- Trouble remembering things 189
- Numbness or tingling 179
- Reduced sense of touch 178
You should not take buspirone if you are taking a monoamine oxidase inhibitor (MAOI) antidepressant or have taken one in the past 14 days. Do not start buspirone if you are being treated with linezolid or intravenous methylene blue because of the risk of serotonin syndrome. Serotonin syndrome is a very serious condition.
Antidepressants may increase the risk of suicidal thoughts and behaviors in young adults. Your doctor should closely watch you for worsening depression or suicidal thoughts. Fetzima is not approved for use in children.
Tell your doctor if you are pregnant, plan to become pregnant, or are breastfeeding. It is not known if buspirone will harm your unborn baby. Buspirone may pass into breast milk.
Tell your doctor if you are pregnant or plan to become pregnant. Using Fetzima in the last months of pregnancy may cause problems in the newborn. There is a pregnancy registry for women who take antidepressants during pregnancy.
Also Compare, Nearby Drugs
Compare levomilnacipran with
How to Read This buspirone vs levomilnacipran Comparison
buspirone is classified in the Azapirone Anxiolytic drug class, while levomilnacipran sits within the Serotonin-Norepinephrine Reuptake Inhibitor (SNRI) class. Drugs from different classes work through distinct mechanisms, so a head-to-head comparison illustrates trade-offs rather than equivalence. Both drugs are prescription-only, so a licensed provider must authorize use.
Adverse event totals above are pulled from the FDA's Adverse Event Reporting System (FAERS). For these top-ranked reactions alone, buspirone has 3,355 submissions while levomilnacipran has 964. Those figures reflect cumulative reporting volume, not per-patient risk, so older, widely dispensed drugs typically look worse on count alone. These two drugs have a known minor interaction flagged in FDA labeling, attributed to both of these medicines increase the levels of a brain chemical called serotonin. taking them together can cause serotonin levels to become dangerously high.. Serious warnings, pregnancy guidance, and contraindications can differ even when indications overlap.
A table cannot substitute for clinical judgment. Effectiveness, tolerability, drug-drug interactions with your other medications, kidney and liver function, pregnancy status, insurance formulary, and price all feed into a decision that only a licensed prescriber can make responsibly. Data here is sourced from FDA Structured Product Labels (SPL) and FAERS, both of which update as manufacturers and clinicians submit new information. This page is for educational purposes only, is not medical advice, and should not be used to self-switch between buspirone and levomilnacipran - always consult your physician or pharmacist first.
Important: This comparison is for informational purposes only. Drug effects vary between individuals. Always consult your doctor or pharmacist for personalized medical advice.