brexpiprazole vs rosuvastatin

According to this portal's Publishing Organization, this page was last reviewed in August 2026 against our methodology. Figures and extracts on this site, including tables above 1,000 rows when the corpus is that large, are the publisher's responsibility.

Side-by-side comparison of brexpiprazole and rosuvastatin. Data from FDA drug databases (Orange Book, NDC Directory, recalls, shortages) covering 20,000+ approved drugs, plus CMS pricing; see our methodology.

minor Known Drug Interaction

Additionally, no dosage adjustment for substrates of CYP2D6 (e.g., dextromethorphan), CYP3A4 (e.g., lovastatin), CYP2B6 (e.g., bupropion), BCRP (e.g., rosuvastatin), or P-gp (e.g., fexofenadine) is required when administered concomitantly with REXULTI.

Drug Class
brexpiprazole Atypical Antipsychotic
rosuvastatin HMG-CoA Reductase Inhibitor (Statin)
Type
brexpiprazole Prescription
rosuvastatin Prescription
Summary
brexpiprazole

Rexulti is a medication used to treat certain mental health conditions. It can help with depression, schizophrenia, and agitation related to Alzheimer's disease.

rosuvastatin

Rosuvastatin is a drug that lowers cholesterol. It helps to reduce the risk of heart problems and stroke.

What It Treats
brexpiprazole

Rexulti can be used with antidepressants to treat major depressive disorder in adults. It can also treat schizophrenia in adults and children 13 years and older. Additionally, Rexulti can help manage agitation in people with dementia due to Alzheimer's disease. Rexulti should not be used as needed for agitation related to dementia.

rosuvastatin

Rosuvastatin is used to lower bad cholesterol (LDL) in adults and children. It can also slow down the hardening of arteries in adults. This medicine also treats high triglycerides and certain inherited cholesterol disorders.

How It Works
brexpiprazole

Rexulti affects the balance of certain natural chemicals in the brain. These chemicals, called neurotransmitters, include dopamine and serotonin. By affecting these chemicals, Rexulti can help improve mood, thinking, and behavior.

rosuvastatin

Rosuvastatin belongs to a class of drugs called statins. It works by blocking a substance your body needs to make cholesterol. This helps to lower your cholesterol levels.

Common Side Effects
brexpiprazole
  • Weight gain
  • Feeling sleepy
  • Restlessness or feeling like you need to move
rosuvastatin
  • Headache
  • Nausea
  • Muscle pain
  • Weakness
  • Constipation
FAERS Reports
brexpiprazole
  • Weight Increased 1,673
  • Akathisia 854
  • Tremor 630
  • Anxiety 591
  • Tardive Dyskinesia 590
rosuvastatin
  • Fatigue 11,700
  • Nausea 10,039
  • Dyspnoea 9,208
  • Diarrhoea 9,198
  • Myalgia 8,784
Serious Warnings
brexpiprazole

Elderly patients with dementia-related psychosis who are treated with antipsychotic drugs have an increased risk of death. Rexulti is not approved to treat dementia-related psychosis unless it is related to agitation from Alzheimer's disease. Antidepressants may increase the risk of suicidal thoughts and behaviors in young adults and children. Tell your doctor right away if you have thoughts of harming yourself.

rosuvastatin

Rosuvastatin can cause muscle problems, including muscle pain, tenderness, or weakness. Tell your doctor right away if you have these symptoms, especially if you also have a fever or feel sick. Rosuvastatin can also cause liver problems. Your doctor may do blood tests to check your liver before and during treatment.

Pregnancy
brexpiprazole

Tell your doctor if you are pregnant or plan to become pregnant. Babies born to mothers who take Rexulti in the last 3 months of pregnancy may have withdrawal symptoms or other problems after birth. There is a pregnancy registry to monitor outcomes in women exposed to Rexulti during pregnancy. You can contact the registry at 1-866-961-2388.

rosuvastatin

Do not take rosuvastatin if you are pregnant. It can harm your unborn baby. Talk to your doctor about other ways to control your cholesterol during pregnancy. Breastfeeding is not recommended while taking rosuvastatin.

Also Compare, Nearby Drugs

How to Read This brexpiprazole vs rosuvastatin Comparison

brexpiprazole is classified in the Atypical Antipsychotic drug class, while rosuvastatin sits within the HMG-CoA Reductase Inhibitor (Statin) class. Drugs from different classes work through distinct mechanisms, so a head-to-head comparison illustrates trade-offs rather than equivalence. Both drugs are prescription-only, so a licensed provider must authorize use.

Adverse event totals above are pulled from the FDA's Adverse Event Reporting System (FAERS). For these top-ranked reactions alone, brexpiprazole has 4,338 submissions while rosuvastatin has 48,929. Those figures reflect cumulative reporting volume, not per-patient risk, so older, widely dispensed drugs typically look worse on count alone. These two drugs have a known minor interaction flagged in FDA labeling, attributed to brexpiprazole does not interfere with the specific proteins the body uses to move and process rosuvastatin.. Serious warnings, pregnancy guidance, and contraindications can differ even when indications overlap.

A table cannot represent individual circumstances. Data here is sourced from FDA Structured Product Labels (SPL) and FAERS, both of which update as manufacturers and clinicians submit new information. This registry does not provide medical, treatment, substitution, or medication-change directions for brexpiprazole or rosuvastatin.

Registry boundary: This comparison displays source-record fields and does not provide individualized medical direction.