bempedoic acid vs cyclosporine

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Side-by-side comparison of bempedoic acid and cyclosporine. Data from FDA drug databases (Orange Book, NDC Directory, recalls, shortages) covering 20,000+ approved drugs, plus CMS pricing; see our methodology.

minor Known Drug Interaction

Cyclosporine Clinical Impact: Concomitant use of NEXLIZET and cyclosporine increases ezetimibe and cyclosporine concentrations. Intervention: Monitor cyclosporine concentrations in patients receiving NEXLIZET and cyclosporine. In patients treated with cyclosporine, weigh the potential effects of the increased exposure to ezetimibe from concomitant use against the benefits of alterations in lipid levels provided by NEXLIZET.

Drug Class
bempedoic acid ACL Inhibitor
cyclosporine Calcineurin Inhibitor (Immunosuppressant)
Type
bempedoic acid Prescription
cyclosporine Prescription
Summary
bempedoic acid

No summary available.

cyclosporine

Vevye eye drops contain cyclosporine. They help treat the signs and symptoms of dry eye disease.

What It Treats
bempedoic acid

Information not available.

cyclosporine

Vevye treats the signs and symptoms of dry eye disease. Dry eye can cause discomfort, stinging, and blurred vision. This medicine can help reduce these symptoms.

How It Works
bempedoic acid

Information not available.

cyclosporine

Vevye contains cyclosporine, which is an immunosuppressant. It works by decreasing inflammation in the eyes. This helps your eyes make more tears.

Common Side Effects
bempedoic acid
  • Upper respiratory tract infection
  • Muscle spasms
  • High uric acid levels in the blood
  • Back pain
  • Stomach pain or discomfort
cyclosporine
  • Irritation where the drops are applied (8%)
FAERS Reports
bempedoic acid
  • Myalgia 335
  • Arthralgia 214
  • Muscle Spasms 153
  • Pain In Extremity 135
  • Nausea 130
cyclosporine
  • Eye Irritation 7,786
  • Pyrexia 4,064
  • Eye Pain 3,808
  • Nausea 3,623
  • Diarrhoea 3,562
Serious Warnings
bempedoic acid

No specific warnings noted.

cyclosporine

To avoid eye injury or contamination, do not touch the bottle tip to your eye or any other surface. Do not use Vevye while wearing contact lenses. If you wear contacts, remove them before using the drops. You can put them back in 15 minutes after using Vevye.

Pregnancy
bempedoic acid

No pregnancy information available.

cyclosporine

It is not known if Vevye will harm an unborn baby. Talk to your doctor if you are pregnant or plan to become pregnant. Cyclosporine can pass into breast milk after being taken orally, but it is unknown if it passes into breast milk from eye drops. Talk to your doctor if you are breastfeeding.

How to Read This bempedoic acid vs cyclosporine Comparison

bempedoic acid is classified in the ACL Inhibitor drug class, while cyclosporine sits within the Calcineurin Inhibitor (Immunosuppressant) class. Drugs from different classes work through distinct mechanisms, so a head-to-head comparison illustrates trade-offs rather than equivalence. Both drugs are prescription-only, so a licensed provider must authorize use.

Adverse event totals above are pulled from the FDA's Adverse Event Reporting System (FAERS). For these top-ranked reactions alone, bempedoic acid has 967 submissions while cyclosporine has 22,843. Those figures reflect cumulative reporting volume, not per-patient risk, so older, widely dispensed drugs typically look worse on count alone. These two drugs have a known minor interaction flagged in FDA labeling, attributed to taking these two medicines together causes the levels of both drugs to rise in your blood.. Serious warnings, pregnancy guidance, and contraindications can differ even when indications overlap.

A table cannot represent individual circumstances. Data here is sourced from FDA Structured Product Labels (SPL) and FAERS, both of which update as manufacturers and clinicians submit new information. This registry does not provide medical, treatment, substitution, or medication-change directions for bempedoic acid or cyclosporine.

Registry boundary: This comparison displays source-record fields and does not provide individualized medical direction.