atomoxetine vs omeprazole
Side-by-side comparison of atomoxetine and omeprazole. Data from FDA drug databases (Orange Book, NDC Directory, recalls, shortages) covering 20,000+ approved drugs, plus CMS pricing; see our methodology.
minor Known Drug Interaction
7.9 Drugs that Affect Gastric pH Drugs that elevate gastric pH (magnesium hydroxide/aluminum hydroxide, omeprazole) had no effect on atomoxetine bioavailability.
Recommendation: No special changes are needed when taking these two drugs together.
Strattera
Prilosec
Atomoxetine (Strattera) is a medicine that can help people with Attention-Deficit/Hyperactivity Disorder (ADHD). It works by affecting a chemical in the brain called norepinephrine.
Omeprazole (Prilosec) is a medicine that reduces the amount of acid in your stomach. It belongs to a class of drugs called proton pump inhibitors (PPIs).
Atomoxetine is used to treat Attention-Deficit/Hyperactivity Disorder (ADHD). ADHD can cause you to be hyperactive, impulsive, and have trouble paying attention. This medicine can help you focus, be less impulsive, and feel calmer. It is for both kids and adults.
This medicine treats frequent heartburn, which is heartburn that occurs 2 or more days a week. It is not meant to give you immediate relief from heartburn. It may take 1 to 4 days for the medicine to fully work.
Atomoxetine works by increasing the amount of norepinephrine in your brain. Norepinephrine is a chemical that helps you pay attention and control your impulses. By increasing norepinephrine, atomoxetine can improve ADHD symptoms.
Omeprazole works by blocking the production of acid in your stomach. It does this by targeting the cells that make stomach acid. This helps to reduce heartburn symptoms.
- • Feeling sick to your stomach
- • Throwing up
- • Feeling tired
- • Not feeling hungry
- • Belly pain
- • Headache
- Feeling sick to your stomach 431
- Head pain 407
- Feeling tired 401
- The health problem got worse 395
- High blood pressure 388
- Tiredness 19,903
- Feeling sick to your stomach 19,841
- Loose stools 19,625
- Difficulty breathing 16,336
- Headache 14,629
Atomoxetine can increase the risk of suicidal thoughts in children and teenagers. Watch carefully for worsening mood or any unusual changes in behavior. Tell your doctor right away if you have any suicidal thoughts or feelings.
Children under 18 should ask a doctor before use. Heartburn in children may be a sign of a serious condition.
Tell your doctor if you are pregnant or plan to become pregnant. It is not known if atomoxetine will harm your unborn baby. There is a pregnancy registry for women who take ADHD medicines during pregnancy. Talk to your doctor about how to register.
Talk to your doctor if you are pregnant or breastfeeding before taking this medicine. It is important to weigh the benefits and risks with your doctor.
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How to Read This atomoxetine vs omeprazole Comparison
atomoxetine is classified in the Selective Norepinephrine Reuptake Inhibitor drug class, while omeprazole sits within the Proton Pump Inhibitor (PPI) class. Drugs from different classes work through distinct mechanisms, so a head-to-head comparison illustrates trade-offs rather than equivalence. Both drugs are split between OTC and prescription status, which affects access and supervision.
Adverse event totals above are pulled from the FDA's Adverse Event Reporting System (FAERS). For these top-ranked reactions alone, atomoxetine has 2,022 submissions while omeprazole has 90,334. Those figures reflect cumulative reporting volume, not per-patient risk, so older, widely dispensed drugs typically look worse on count alone. These two drugs have a known minor interaction flagged in FDA labeling, attributed to omeprazole changes the acid levels in the stomach, but this does not change how the body absorbs atomoxetine.. Serious warnings, pregnancy guidance, and contraindications can differ even when indications overlap.
A table cannot substitute for clinical judgment. Effectiveness, tolerability, drug-drug interactions with your other medications, kidney and liver function, pregnancy status, insurance formulary, and price all feed into a decision that only a licensed prescriber can make responsibly. Data here is sourced from FDA Structured Product Labels (SPL) and FAERS, both of which update as manufacturers and clinicians submit new information. This page is for educational purposes only, is not medical advice, and should not be used to self-switch between atomoxetine and omeprazole - always consult your physician or pharmacist first.
Important: This comparison is for informational purposes only. Drug effects vary between individuals. Always consult your doctor or pharmacist for personalized medical advice.