amoxicillin vs estradiol
Side-by-side comparison of amoxicillin and estradiol. Data from FDA drug databases (Orange Book, NDC Directory, recalls, shortages) covering 20,000+ approved drugs, plus CMS pricing; see our methodology.
minor Known Drug Interaction
Following administration of amoxicillin to pregnant women, a transient decrease in plasma concentration of total conjugated estriol, estriol-glucuronide, conjugated estrone, and estradiol has been noted.
Recommendation: Talk to your doctor about whether you need to use extra protection or if your hormone levels need to be checked.
Amoxil
Estrace, Vivelle-Dot
Amoxicillin and Clavulanate Potassium is a combination medicine used to fight bacterial infections. It contains amoxicillin, an antibiotic, and clavulanate, which helps the amoxicillin work better.
Iclevia is a birth control pill. It contains two hormones, a progestin and an estrogen, that work together to prevent pregnancy.
This medicine treats infections like lower respiratory infections, ear infections (otitis media), sinus infections, skin infections, and urinary tract infections. It works against specific bacteria that cause these infections. However, it should only be used when tests show the bacteria are susceptible to it, to avoid antibiotic resistance.
Iclevia is used by women who can get pregnant to prevent pregnancy. It contains two types of hormones. These hormones stop you from releasing an egg and also change the lining of your uterus, which prevents pregnancy.
Amoxicillin kills bacteria by stopping them from building cell walls. Some bacteria produce a substance called beta-lactamase, which can destroy amoxicillin. Clavulanate blocks beta-lactamase, allowing amoxicillin to effectively kill the bacteria.
Iclevia contains two hormones: levonorgestrel (a progestin) and ethinyl estradiol (an estrogen). These hormones prevent pregnancy by stopping ovulation (the release of an egg from the ovary). They also change the lining of the uterus to prevent a fertilized egg from implanting.
- • Diarrhea or loose stools
- • Nausea
- • Skin rashes
- • Hives
- • Vomiting
- • Headache
- • Heavy menstrual bleeding
- • Nausea
- • Painful periods
- • Acne
- Long-term kidney disease 4,661
- Sudden kidney damage 4,200
- Diarrhea 4,083
- Allergic reaction to the medicine 3,744
- Feeling sick to your stomach 3,700
- The product did not stick properly 5,172
- Headache 5,035
- Nausea 4,752
- Tiredness 4,511
- Pain 3,478
This medicine can cause serious allergic reactions, including fatal ones. Stop taking it and get medical help right away if you have any signs of an allergic reaction. This medicine can also cause severe skin reactions. Tell your doctor if you develop a rash. It can also cause liver problems and severe diarrhea.
Cigarette smoking increases your risk of serious heart problems from birth control pills. This risk is higher if you are over 35 and smoke more cigarettes. You should not take Iclevia if you are over 35 and smoke.
Tell your doctor if you are pregnant or plan to become pregnant. It is not known if this medicine will harm your unborn baby. Amoxicillin passes into breast milk and may cause harm to a nursing infant. Talk to your doctor before breastfeeding.
Do not use Iclevia if you are pregnant. If you become pregnant while taking Iclevia, stop taking it right away. Iclevia can reduce milk production, so you may want to use a different birth control method while breastfeeding.
How to Read This amoxicillin vs estradiol Comparison
amoxicillin is classified in the Penicillin Antibiotic drug class, while estradiol sits within the Estrogen Hormone class. Drugs from different classes work through distinct mechanisms, so a head-to-head comparison illustrates trade-offs rather than equivalence. Both drugs are prescription-only, so a licensed provider must authorize use.
Adverse event totals above are pulled from the FDA's Adverse Event Reporting System (FAERS). For these top-ranked reactions alone, amoxicillin has 20,388 submissions while estradiol has 22,948. Those figures reflect cumulative reporting volume, not per-patient risk, so older, widely dispensed drugs typically look worse on count alone. These two drugs have a known minor interaction flagged in FDA labeling, attributed to taking this antibiotic can temporarily lower the amount of estrogen hormones circulating in your blood.. Serious warnings, pregnancy guidance, and contraindications can differ even when indications overlap.
A table cannot substitute for clinical judgment. Effectiveness, tolerability, drug-drug interactions with your other medications, kidney and liver function, pregnancy status, insurance formulary, and price all feed into a decision that only a licensed prescriber can make responsibly. Data here is sourced from FDA Structured Product Labels (SPL) and FAERS, both of which update as manufacturers and clinicians submit new information. This page is for educational purposes only, is not medical advice, and should not be used to self-switch between amoxicillin and estradiol - always consult your physician or pharmacist first.
Important: This comparison is for informational purposes only. Drug effects vary between individuals. Always consult your doctor or pharmacist for personalized medical advice.