amlodipine/valsartan vs heparin
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Side-by-side comparison of amlodipine/valsartan and heparin. Data from FDA drug databases (Orange Book, NDC Directory, recalls, shortages) covering 20,000+ approved drugs, plus CMS pricing; see our methodology.
minor Known Drug Interaction
Valsartan Agents Increasing Serum Potassium: Concomitant use of valsartan with other agents that block the renin-angiotensin system, potassium-sparing diuretics (e.g., spironolactone, triamterene, amiloride), potassium supplements, salt substitutes containing potassium or other drugs that may increase potassium levels (e.g., heparin) may lead to increases in serum potassium and in heart failure patients to increases in serum creatinine.
Exforge
Heparin Sodium
Exforge HCT is a combination medicine used to treat high blood pressure. It contains amlodipine, valsartan, and hydrochlorothiazide to help lower your blood pressure.
Heparin is a medicine that helps prevent and treat blood clots. It is given as an injection into a vein or under the skin.
Exforge HCT is used to treat high blood pressure. Lowering blood pressure reduces the risk of heart problems and strokes. It is for people who need more than one medicine to control their blood pressure. It is not for the initial treatment of high blood pressure.
Heparin is used to prevent and treat blood clots in your veins and lungs. It can also prevent clots after surgery or if you have an irregular heartbeat called atrial fibrillation. Heparin can also treat blood clotting problems throughout your body and prevent clots during surgery, blood transfusions, or dialysis.
This medicine works in three ways to lower blood pressure. Amlodipine relaxes your blood vessels. Valsartan blocks a substance that tightens blood vessels. Hydrochlorothiazide helps your body get rid of extra salt and water.
Heparin works by stopping certain proteins in your blood from forming clots. It helps to thin your blood and prevent new clots from forming. It does not dissolve existing blood clots, but it can keep them from getting bigger.
- • Dizziness
- • Swelling in your arms, hands, legs, and feet
- • Headache
- • Heartburn
- • Tiredness
- • Bleeding
- • Irritation at the injection site
- • Allergic reactions
- • Increased liver enzyme levels
- Pain 11
- Interaction with another medicine 9
- Taking too much medicine on purpose 9
- Attempt to end one's own life 9
- Weight loss 9
- Heparin-Induced Thrombocytopenia 1,207
- Nausea 708
- Drug Hypersensitivity 603
- Vomiting 572
- Hypotension 547
If you are pregnant, stop taking Exforge HCT right away. This medicine can harm or kill your unborn baby.
Heparin can cause serious bleeding, which can be fatal. It can also cause a severe reaction called heparin-induced thrombocytopenia (HIT), where your body attacks your own platelets. Make sure your doctor knows if you have ever had HIT. Using the wrong strength of heparin can also cause fatal bleeding.
Do not take Exforge HCT if you are pregnant. It can cause serious harm to your unborn baby, including death. Breastfeeding is not recommended while taking this medicine.
If you are pregnant, talk to your doctor about the risks and benefits of using heparin. Preservative-free heparin is recommended during pregnancy if available. It is not known if heparin passes into breast milk, so it is recommended to avoid breastfeeding while using this medicine.
How to Read This amlodipine/valsartan vs heparin Comparison
amlodipine/valsartan is classified in the CCB / ARB Combination drug class, while heparin sits within the Unfractionated Heparin class. Drugs from different classes work through distinct mechanisms, so a head-to-head comparison illustrates trade-offs rather than equivalence. Both drugs are prescription-only, so a licensed provider must authorize use.
Adverse event totals above are pulled from the FDA's Adverse Event Reporting System (FAERS). For these top-ranked reactions alone, amlodipine/valsartan has 47 submissions while heparin has 3,637. Those figures reflect cumulative reporting volume, not per-patient risk, so older, widely dispensed drugs typically look worse on count alone. These two drugs have a known minor interaction flagged in FDA labeling, attributed to both medications can cause potassium levels in your blood to rise, which can affect your heart and kidneys.. Serious warnings, pregnancy guidance, and contraindications can differ even when indications overlap.
A table cannot represent individual circumstances. Data here is sourced from FDA Structured Product Labels (SPL) and FAERS, both of which update as manufacturers and clinicians submit new information. This registry does not provide medical, treatment, substitution, or medication-change directions for amlodipine/valsartan or heparin.
Registry boundary: This comparison displays source-record fields and does not provide individualized medical direction.