PlainMeds provides educational information only. This is not medical advice. Always consult your doctor or pharmacist.

amikacin vs meropenem

Side-by-side comparison of amikacin and meropenem Data from FDA drug databases (Orange Book, NDC Directory, recalls, shortages) covering 20,000+ approved drugs, plus CMS pricing; see our methodology.

Drug Class
amikacin Aminoglycoside Antibiotic
meropenem Carbapenem Antibiotic
Type
amikacin Prescription
meropenem Prescription
Summary
amikacin

Amikacin is an antibiotic medicine. It fights serious infections caused by certain types of bacteria.

meropenem

Meropenem is an antibiotic medicine. It fights bacteria in your body to treat different kinds of infections.

What It Treats
amikacin

Amikacin treats serious infections caused by bacteria. This includes infections in the blood, lungs, bones, joints, brain, skin, and abdomen. It can also treat burns, post-surgery infections, and complicated urinary tract infections.

meropenem

Meropenem treats complicated skin infections in adults and kids 3 months and older. It also treats complicated infections in the stomach area for adults and kids. In children 3 months and older, it can treat bacterial meningitis (an infection of the brain and spinal cord).

How It Works
amikacin

Amikacin belongs to a class of drugs called aminoglycosides. It works by stopping the growth of bacteria. This helps your body fight off the infection.

meropenem

Meropenem belongs to a class of drugs called carbapenem antibiotics. It works by stopping the growth of bacteria. This helps your body fight off the infection.

Common Side Effects
amikacin

No common side effects listed.

meropenem
  • Headache
  • Nausea
  • Constipation
  • Diarrhea
  • Anemia
FAERS Reports
amikacin
  • Off Label Use 1,908
  • Drug Ineffective 1,673
  • Cough 1,620
  • Dyspnoea 1,556
  • Hospitalisation 1,360
meropenem
  • Drug Ineffective 4,220
  • Off Label Use 3,119
  • Pyrexia 2,090
  • Pneumonia 1,435
  • Sepsis 1,364
Serious Warnings
amikacin

Amikacin can potentially cause hearing loss and kidney damage. Tell your doctor if you have kidney problems or are taking other medicines that can affect your hearing or kidneys. Your doctor should closely monitor you for hearing and kidney problems during treatment. This drug can also cause muscle weakness or breathing problems, especially if you are also taking anesthesia or certain muscle relaxants.

meropenem

You should not take this medicine if you are allergic to meropenem or similar antibiotics. This drug may cause serious allergic reactions, including trouble breathing. Meropenem can also cause seizures, especially if you have kidney problems or a history of seizures. Diarrhea can occur, and could be a sign of a serious infection in your colon.

Pregnancy
amikacin

Tell your doctor if you are pregnant or breastfeeding. Amikacin may harm your unborn baby. It is not known if amikacin passes into breast milk.

meropenem

It is not known if meropenem will harm your unborn baby. Meropenem can pass into breast milk. Talk to your doctor about the risks and benefits of using this medicine if you are pregnant or breastfeeding.

Also Compare — Nearby Drugs

How to Read This amikacin vs meropenem Comparison

amikacin is classified in the Aminoglycoside Antibiotic drug class, while meropenem sits within the Carbapenem Antibiotic class. Drugs from different classes work through distinct mechanisms, so a head-to-head comparison illustrates trade-offs rather than equivalence. Both drugs are prescription-only, so a licensed provider must authorize use.

Adverse event totals above are pulled from the FDA's Adverse Event Reporting System (FAERS). For these top-ranked reactions alone, amikacin has 8,117 submissions while meropenem has 12,228. Those figures reflect cumulative reporting volume — not per-patient risk — so older, widely dispensed drugs typically look worse on count alone. No direct interaction between these two drugs is listed in our FDA-derived dataset, though co-prescription still warrants pharmacist review. Serious warnings, pregnancy guidance, and contraindications can differ even when indications overlap.

A table cannot substitute for clinical judgment. Effectiveness, tolerability, drug-drug interactions with your other medications, kidney and liver function, pregnancy status, insurance formulary, and price all feed into a decision that only a licensed prescriber can make responsibly. Data here is sourced from FDA Structured Product Labels (SPL) and FAERS, both of which update as manufacturers and clinicians submit new information. This page is for educational purposes only, is not medical advice, and should not be used to self-switch between amikacin and meropenem — always consult your physician or pharmacist first.

Important: This comparison is for informational purposes only. Drug effects vary between individuals. Always consult your doctor or pharmacist for personalized medical advice.